Hi, I've been 200mg of Pristiq for major depression, when my dose was upped I noticed I was getting a very stiff, very sore middle back and this is now causing other skeletal and muscular pain elsewhere. Has anybody else experienced this? It's been good for my depression and consistency of work and thought but the back pain has been really hard to manage and is in danger of making me depressed. I get regular Osteo and massage.