My doctor says yes, but I am concerned about the warning's of serotonin shock even though these drugs/herbs work on different parts of the brain. Has anyone tried this combination or are you a doctor who would be willing to weigh in on this question? thanks so much
Can I take st. John's wort with Welbutrin?
Question posted by leighanson on 1 March 2011
Last updated on 2 March 2011
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3 Answers
vincent1905
2 March 2011
Hi , I had taken that one time and I had a bad reaction to it. My doctor said it was good but some people get bad reactions to it like I did. You could try it and it may not bother you like it did me. Everyone reacts different. Stay in touch
till33
2 March 2011
not a good idea i took it with prozac and gotsomething called seretoninin syndrome i went into seizures throwing up major headache,thats what happen when you get to much seretoni.but im really not sure with that med it mainly works on norepinephrine and dopamine you should ask your doc or pharmacistt
Inactive
1 March 2011
Interactions between your selected drugs
No results found - however, this does not necessarily mean no interactions exist. ALWAYS consult with your doctor or pharmacist.
Other drugs that your selected drugs interact with
st. john's wort interacts with more than 300 other drugs.
Wellbutrin (bupropion) interacts with more than 300 other drugs.
Interactions between your selected drugs and food
st. john's wort ↔ food
Applies to: st. john's wort
GENERALLY AVOID: An isolated case report suggests that foods containing large amounts of tyramine may precipitate a hypertensive crisis in patients treated with St. John's wort. The mechanism of interaction is unknown, as St. John's wort is not thought to possess monoamine oxidase (MAO) inhibiting activity at concentrations achieved in vivo. The case patient was a 41-year-old man who had been taking St. John's wort for seven days prior to presentation at the emergency room with confusion and disorientation. The patient recalled last eating aged cheese and having a glass of red wine approximately 10 hours prior to admission. No other cause of delirium or hypertension could be identified.
MANAGEMENT: Until further information is available, patients treated with St. John's wort should consider avoiding consumption of protein foods in which aging or breakdown of protein is used to increase flavor. These foods include cheese (particularly strong, aged or processed cheeses), sour cream, wine (particularly red wine), champagne, beer, pickled herring, anchovies, caviar, shrimp paste, liver (particularly chicken liver), dry sausage, figs, raisins, bananas, avocados, chocolate, soy sauce, bean curd, yogurt, papaya products, meat tenderizers, fava beans, protein extracts, and dietary supplements. Caffeine may also precipitate hypertensive crisis so its intake should be minimized as well.
https://www.drugs.com/interactions-check.php?drug_list=2106-0,440-203
All the best and take care.-
leighanson
3 March 2011
hi all, thanks so much for your comments and answers... I have to say, VERY HELPFUL. I can't seem to get a "straight" answer from any doctor, so I think it's best to avoid for the time being, considering your responses and the research I've discovered... it seems quite possible to be, not just an uncomfortable, but potentially dangerous combination. I just found this site 2 days ago and am grateful to have found it. thanks again.
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wellbutrin sr, depression, shock, st. john's wort
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