My daughter was on 30 mg of Cymbalta for 7 to 8 weeks and was doing ok until about a week or two ago, when she started to be more irritable, angry, frustarted and depressed. She is struggling with why is she suddenly moody again. We saw her thereapist and psychaitrist who increased her dose to 60mg of Cymbalta and kept her Seroquel at the 200mg at bedtime.

I just read a review on this site by a 15 year old girl who indicated that the Cymbalta work for the first few months (3) and then suddenly stopped. Can this happen? Would this be normal? I am new to this and trying to understand it all and understand how it all works.