Bystolic 5 mg = very bad side effects for me. How long before out of my system?
Question posted by cdubya on 26 Feb 2011
Last updated on 24 September 2018
Usually 2-3 days.
I realize this answer is very late but may help someone in future.
Nebivolol is metabolized by a number of routes, including glucuronidation and hydroxylation by CYP2D6. The active isomer (d-nebivolol) has an effective half-life of about 12 hours in CYP2D6 extensive metabolizers (most people), and 19 hours in poor metabolizers and exposure to d-nebivolol is substantially increased in poor metabolizers. This has less importance than usual, however, because the metabolites, including the hydroxyl metabolite and glucuronides (the predominant circulating metabolites), contribute to β-blocking activity.
It takes 5.5 x elimination half life for a medicine to be cleared from ones system. Therefore if we use the longer half life of 19 hours then it should take approximately 105 hours (5.5 x 19 hours) for Bystolic to be cleared from ones system.
- Bystolic uses and safety info
- Bystolic information for Healthcare Professionals (includes dosage details)
- Side effects of Bystolic (detailed)
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