Honestly for me klonopins do not work I'd rather take .5 mg of ativan over and mg of klonopins ... I've just been perscribed klonopins after being on ativan and once again I'm suffering from anxiety but everyone's different I have generalized anxiety disorder (GAD) and panic disorder so maybe that's why it doesn't work for me I don't know...
Unlike Klonopin, Ativan has very low lipid solubility. This causes it to stay in the vascular compartment. As a result, you will experience peak effects from Ativan for 6-12 hours. Ativan's elimation half life is 9-20 hrs. Klonopin has a longer half life at 50 hrs. but with its high lipid solubility, it quickly breaks the blood-brain barrier, and peak effects are closer to only 1-2 hrs. The two agents are more or less "cousins" & one being stronger than the other may not mean it will work better. For further info, reasearch the pharmacokinetics of each agent.
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