Anyone having trouble switching generic Ativan (lorazepam)?
Question posted by JayhawkJourney on 30 May 2013
Last updated on 17 January 2023
Have been taking one half of a 0.5mg lorazepam for years. Lately the Sandoz brand. My pharmacy can no longer get that brand (not sure if Sandoz still makes it). I was given Watson instead. It gave me bad heartburn and when it finally kicked in it felt so strong I was unable to stand up. I asked for a different brand and was given Mylan. It was way too strong. I felt like I had a brick in my chest and developed a sore throat and horrible dry mouth and lips. My lips are cracked from one dose.
I called a different pharmacy and they assured me they had Sandoz. Had to get a new prescription from my doc. When I got the new pills they told me they were Sandoz but they are really Actavis. I assume Sandoz purchased Actavis. I've taken one dose of this with not much relief and it is bothering my stomach.
I know brand names are usually better but I was doing okay before the switch. Do they still make a brand name Ativan or the Sandoz brand? Anyone know?
I am really having a hard time with this as Ativan/lorazepam is the only med I have been able to take for anxiety and panic with low side effects until now. I've tried many things through the years.
I don't understand why the generics are allowed to be so different and have so many inactive ingredients.
Yes I just picked up my prescription for 1 mg three times a day the lorazepam it’s not working at all I’m kind of at a loss I can’t sleep I’m real edgy where can I send or have this medication checked to see actually what’s really in it it has no taste I don’t understand this I wanna get this medication checked out
11 Sep 2021
I’ve had real issues with the generic Leading, to the point I’ve thought about having it tested for content. It’s like getting a placebo. Medications for anxiety and seizure should contain the medication they’re supposed to!
8 Feb 2020
Here on the West Coast they still have Sandoz and Actavis. If you wanted the name brand Ativan its very expensive. The Leading brand is not so good. My pain management Dr in fact told me so many generics do not work as they're not putting enough of what works into them, as I agree. Also when they went from yellow Norco's and made them white they no longer worked the way the yellow Norco did, they claim all they did was took the color out, I'm not so sure I believe that :(
20 Dec 2019
I am so relieved to read that others are going through what myself and my mother and husband are experiencing. Ive been taking the same dose of lorazepam made by Watson for 16 years; never ever went over my regular dose. In the last 6 months I have had such a difficult time because now Activist bought Watson, and the medicine is not effective. I wake up at night, Im shaky, constantly anxious, and I can't focus at work. My mother wakes up in the middle of the night, and my husband says it has no effect on him. I have called every pharmacy in the area, even out of the area, and Activist is the only one who makes it. I have even bought the brand name for my family and it is $35.00 per pill, and it works fine, but Im not going to pay (or afford) that amount. When I ask the pharmacist if anyone else has complained, they say, "Oh no, absolutely not. " I just know that isn't true.
I called my doctor and asked to switch to Xanax because I cant continue running in circles and feeling so scattered. Ive been on Xanax for 2 days, and its been much better, but its not the same, I just feel 'blah'. Maybe it takes time. I'm disgusted with what the generic drug companies are doing, because there are 2 other drugs (blood pressure and prozac) in which I have to purchase the brand name. ... Thank you so much for this blog!! I was feeling like I was overly sensitive.
11 Oct 2019
Yep..I've been on Activis brand for over 8 months now and it works great for me. See a lot of complaints about it, but no issues here with it. Filled a script and took as normal for two days and noticed it just wasnt working the same AT ALL... and I had stomach issues those days... finally looked at bottle and it was LEADING brand. I do believe some things are placebo effects, especially people with anxiety disorders and people who read tons of negative stuff on the internet and put it in their head there is a problem... it happens... but I had NO idea i had a different brand or even that they would do that to someone... so definitely different ingredients in the different generics. I was able to switch them out but they tried to tell me they are the same thing. Nope, sorry. Now when I put in my refill, i add to please have it Activis brand, thanks. ha.
11 Oct 2019
I am having a really hard time switching from Mylan 1mg Lorazepam. Have been on it for 6 years with no problems. Now I can’t find it. I tried Aurobindo and I am having severe anxiety and insomnia. Please help.
What is most similar to Mylan? Can you buy it in Canada or overseas? Can a compound pharmacy make the same exact formulation?
29 June 2019
I picked up my prescription for Lorazepam. The pharmacist said it is a new manufacturer. The pills use to help with my anxiety and sleep. I haven’t slept for 4 nights. The pills don’t work anymore. I feel like the new manufacturer gave me a placebo.
13 Feb 2019
YES, and YES. This is RIDICULOUS. 3 months in a row I am left to scramble and find another generic for lorazepam since Mylan and Watson no longer make it. Preferred Pharma is (in my experience) placebo - it's sugar. Doesn't do a darn thing. I truly believe we need to rally together and start to get the FDA behind us. Anxiety is real. We shouldn't have to go through this. I'm at wits end and don't know what I'm going to do. Brand Ativan is just too expensive - $2.5k/mo that's insane. I agree with another commenter, if this were for diabetes or some other ailment, it would be handled. Why are they not treating this with the same regard???
1 Feb 2019
I don't think anybody is manufacturing the old generic lorazepam anymore. What I am referring to is one without side effects you mentioned. I also have had heartburn.. In addition, I have constant foot pain with the 2 milligram dosage and that's after splitting it into 4 parts.. .5 dose.. The foot pain I'm referring to you is muscular not skeletal.. I had no problems with the old Sardoz brand.. I suspect that they have added fillers to the new generic lorazapams and this is what causes side effects especially gastrointestinal stuff.. I know drug companies have to make money... What I can't fanthom is are they really saving money with a "generic" by adding fillers? If it's not fillers, then why can't they follow the recipe that Sardoz went by? I'd like to know if there are more people suffering from the changed lorazepam manufacturers.. I went from no problems to a problem every night with side effects.
I can't believe that my body changed over night in receiving the drug... I am going to go off the drug and deal with insomnia again if I have to .. The cure is worse than the disease in this case... Please gastrointestinal sufferers report this to your doctor and to the drug companies. Maybe we can affect a change back to Sardoz "recipe"... Thank you
13 Sep 2018
Sept. 2018. Trying to find information about / "Helping my Mom" find " Mylan " type lorazapame" generic equivalent ? 1mg or scored 2mg. Generic. Any info. Would help for "alternate generic . Thanks.
8 Sep 2018
I got some 0.5 mg lorazepam manufactured by Leading Pharma from a CVS in Richmond, VA, in July 2018. I took half of one today after my Mylan brand had almost run out, and got jittery and unsteady. I called my CVS pharmacy and they told me the Mylan was on back order, with a back order date of 9/28/18 for one of the size bottles they dispense it from. I see on this forum reports that Mylan has stopped making lorazepam. So I wonder if the back order that my CVS reported is something that will never materialize.
17 Aug 2018
I contacted Sandoz and they told me they had discontinued making Lorazepam. I asked why and was told it was a marketing decision. Marketing has no idea how many people rely on this drug. For my mother this was the only brand that worked for her. Not sure what we will do since other brands she has tried only work for a couple hours.
9 Aug 2018
Per my telephone calls on 7th August 2018 to both Sandoz (800.525.8747), and Mylan (877.446.3679) corporate east coast offices, they have both DISCONTINUED making lorazepam, a generic of Ativan. Personally, after 5 years on Sandoz 0.5mg, Walgreen switched me to Leading, same dosage. I tried it for 2 months with little results. Whereas Sandoz usually took effect within 15 minutes, Leading took 45 mins. to an hour to kick in, & just made me tired & depressed. I informed my doctor it wasn't working so I am starting Actavis by Watson today, as it seems it's the only other brand available in my city of over one million... hope this works. Will follow thru with an update in a few days. FYI: lorazepam by Actavis is manufactured by: Watson Pharma PVT LTD, Verna, Salcette Goa, 403 722 INDIA. The inactive ingredients are: LACTOSE, magnesium stearate, microcrystalline cellulose, & polacrilin potassium.
Lorazepam by Sandoz was manufactured by: Actavis Pharma Manufacturing PVT LTD, SIDCO Pharmaceutical Complex, Alathur Dist. -603 101 Tamil Nadu, India FOR Sandoz. Lorazepam by Leading is manufactured by: Leading, Fairfield, New Jersey 07004 It tastes sugary and is a far cry from being anywhere close to being as effective as Sandoz. I asked both companies why they 'dicontinued' lorazepam and only Sandoz responded saying, "it was a business decisions." (Big help, right!!! ) Hope this info is useful & helps others clarify some of the questions & rumors going around about the different brands of generic lorazepam. Inhale slowly from your stomach, hold a few seconds, then exhale slowly and have a great day! Look at your feet. You are standing in the sky. When we think of the sky, we tend to look up, but the sky actually begins at the earth.
4 July 2018
I just had to get Watson by actavis lorazepam 1 mg.They had mylan before now it's on back order. I have taken the mylan 1 mg with no problems. I just took Watson yesterday and couldn't sleep at all. I am scared because I have 29 days of pills left unless doctor will write me a new script so I can go to a local place that said they ordered mylan for me. What do you do when you can't sleep and how long can you go without sleep, this has never happened before. If anyone has any suggestions please get back with me because I can't see my doctor until Monday. Why do these pharmacies keep getting different generics that can vary in strength by 20% higher or lower depending on which company makes them and we have to be their guinea pigs.
14 June 2018
Hang in there. A lot of this is just trial and error, there seems to be enough makers of lorazepam, it took me months to find the one that would work, Actavis was perfect , watson is what i use, not great but can get by, not the best way to go through life but better than the anxiety and panic attacks that come with not taking anything, good luck to you, don't give up looking