I started Lamictal about 8 weeks ago and have gained 16 lbs. also my headaches have increased. I was put on it for seizures and headaches and I asked the Neurologist 2 days ago can it make you gain weight, his answer was short and he got aggitated NO. I beg to differ. My ankles and legs are so swollen it hurts to walk, I've had to resort to Lasix on my own which I have a little success so far in the last 2 days, but the Dr. denies everything and acts like I'm crazy.
Lamictal - has anyone had more headaches and fluid retention in legs and ankles and weight gain ?
Question posted by Rhonda62 on 4 Aug 2012
Last updated on 16 August 2022 by WildcatVet
"Very common (10% or more of users): Dizziness (38%), headache (29%)"
"Common (1% to 10% of users): Weight decrease, weight gain"
"Rare (less than 0.1% of users): Bilirubinemia, peripheral edema"
I’ve been on lamictal for 3 weeks (25 mg daily for first week and 50 mg daily after that) I have depression, anxiety, and adhd. I Take adderall 20 mg (3 times a day), Wellbutrin XL 300mg (in the morning), and Xanax .5mg (before bed) and I’ve gained 10 lbs. I’m a 32 year old female I typically weigh 120lbs and I’m 5’4”.
I Found this thread after searching water retention and lamictal online, because I have been noticing, as of 4 days ago, that my legs are shiny, jiggly, look swollen, and hurt, could be water retention.
I will measure the circumference of my legs and wait til the weekend to see if they get bigger.
Lamictal is definitely making me more hungry and it has been harder to get to sleep even with Xanax so i’ll order some thing to eat right before bed and I’m usually craving donuts. Eating makes me tired but not lately.
I take lamictal in the morning now to help with sleep problem and have lowered my dose to 25mg from 50mg as of today.
I’ve also had headaches 4 days the past week that won’t go away for hours, even with 1000mg of acetaminophen.
My depression has slightly improved, but past few days I catch myself zoning out watching tv. Will talk to my doctor about this tomorrow and update if needed.
I am on Lamictal and it has given me my life back. I've gain weight but don't know if it has anything to do with Lamictal. I couldn't eat when I was so anxious and depressed so I lost 30 lbs. I'll take the weight back because I am feeling so good.
I didn't know water retention was a side effect of Lamictal. I surely would have had a fit and told my doctor I wanted off of it if that happened to me: / ( I am so weight conscious). Fortunately, I wasn't on it for too long (I take meds for Epilepsy), I developed a bad rash on my arm, which is one of the signs of allergy, and had to go off of it immediately. After reading the above posts, I'm happy that I was allergic to it!
When I was on Divalproex,my ankles were swollen,my feet and my hands. I stopped taking it because of that. Since i've been on Lamictal the swelling has gone down.
Whenever someone tries to minimalize your symptoms Or complaints I think it's time to seek out another doctor. You won't get the truth from the pharmaceutical company. Don't let anyone tell you what you know and feel is the truth Influence your decision to at least discuss it with a doctor. I have had the same problems myself. Hope this helps. If you can't even discuss your side effects with your doctor There's a problem.
I don't remember gaining weight when I started taking it. I did gain about 40 pounds within the last couple years, but never connected it to lamictal until now, that I'm slowly cutting it down. First of all, I STRONGLY recommend to change doctors. My former psychiatrist prescribed it as a "mood stabilizer that would help with anxiety" (I do have a Generalized Anxiety Disorder), and it made me sick while starting to take it. I have now informed my new shrink that I wanted it out of my system and I've been dropping it by 25mg every two weeks... I had already started to lose weight before, but I literally lost 6 pounds last week as I cut down another 25mg... Most of it has obviously been water. If I see a(n even more) noticeable weight and water retention weight as I continue to cut it down and get to stop taking it, I will let you know.
I started lamictal about 6 months ago. Water retention was horrible. I gained 12 lbs. I since stopped (approximately 1 week ago), have dropped over 3 lbs and can finally remove my rings!! I whole heartedly believe this medication causes water retention and possibly weight gain!
I have gained about 35 pounds since I started taking Lamictal about 3 years ago. I also just visited my doctor because of headaches and fluid in my legs. I know I'm over 40 now, but I really don't eat alot so I am definitely gonna talk to my pdoc about changing from lamictal to something else. I'm kind of scared to get off the lamictal because it has been working very well with my Bi-Polar and I haven't had any severe depression since I been on it.
Yeah the side effects are horrible. What woman can stand to gain weight and feel good about herself? Also the health risks of being overweight are enormous. Its like we have to choose between being mentally healthy or physically healthy. Unfortunately complaints bring on even more disregard and minimalizing.
Hello Rhonda62. In regards to weight gain, between 1 to 5% of people taking Lamictal for Manic Depression/Bi-polar Disorder saw an increase in thier weightt. People taking Lamictal for seizures saw no weight increase. In regards to headaches, close to 29% of people taking Lamacital, reported headaches as a common normal side effect to taking the drug.. All of the above are results from clinical studies. Regards, pledge
Additional comment. Up to 5% of people taking Lamicital for seizures saw a decrease in thier weight, meaning weight loss.
So that means 95 percent of people taking Lamictal for bipolar saw an increase of weight?
Anything is possible with those types of meds. When I was on 2000 mg of Depakote, I gained 25 pounds of water weight in two weeks. I looked like a marshmallow and felt awful. It took a month of lasix to get rid of the weight AFTER I stopped the med. My doc told me the chances of weight gain on Lamictal are less, but as I said any adverse reaction is possible at any time. You might want to call your pharmacist to make sure you are not having a drug interaction with any other meds you are on. Then call the neurologist and make an appointment so he can see your situation. Might be your best best. You are paying him well for his services. You deserve answers.
Do what thou must to get his attention.
Peace and great luck.
Soooo true ! Have been on many of these meds for depression. Not Bipolar am told. I am convinced they all increase weight ( with me anyway). EXCEPT OF COURSE, Wellbutrin causes weight loss. Naturally I had to come off that !!! Trying to come off Cymbalta for FMS and Lamictal with pmd guidance. Rather be thinner and they were not helping after a year anyway !
I would call the pharmacist and ask him if it can cause fluid retention. I didn't find that in the list, but maybe he knows more. Headaches is a side effect. Lamictal usually causes weight loss. Your neurologist takes the prize for jerk of the day on his answer. If the pharmacist says no fluid retention, I would call my primary and make an appt. See what he says. It may be unrelated.
I've been on Lamictal for five months now, when does the weight loss start?
I hope soon...
I lost some, but slowly and almost not noticeably. It seems the ones who lose weight are the ones who can least afford it, so I didn't lose much, lolol..I could have given up about 40, lol
Oh well, I could stand a drop in weight, but I refuse to weigh myself and can tell if I'm losing by how my clothes fit. Go figure!
I felt so good when I was on it, I don't think I'd have fussed, but I think in her case she's got something to worry about.
Believe me even doctors won't find it in the list. They're sold a bill of goods just like we are.
I've only been on Lamotrigine for 6 days so I haven't noticed any change yet in my moods, but I have noticed that my hands and feet seem swollen, and my eyelids are so puffy I can barely get them open sometimes. Has anyone else had this particular problem? Also, how long did it take for the lamotrigine or Lamictal to take effect? I'm not expecting anything big after only 6 days, but the sooner, the better.
lamictal, seizures, weight loss (obesity/overweight), headache, fluid retention, weight
- Lamictal uses and safety info
- Lamictal information for Healthcare Professionals (includes dosage details)
- Side effects of Lamictal (detailed)
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