Can I take antacid with Wellbutrin?

Hi, diazj!
For the most part, yes, you can. You can use the Interaction Checker but you'll need to look at the ingredients in the product you plan on using:
https://www.drugs.com/drug_interactions.html
To be safe be sure to ask your doctor or pharmacist.
Best regards,

Antacids are generally safe to be taken with Wellbutrin. There are a lot of antacids available in the market. If you have a specific antacid medication in mind, you could also check: https://www.drugs.com/interaction/list/?drug_list=440-203

Just input the specific medication and it will be checked for any interaction with Bupropion (Wellbutrin).