IS 25MG ZOLOFT a therapeutic dose for an adult?

I've read that 25mg is a therapeutic dose. I started with Lexapro, then Cymbalta (2 weeks, HORRIBLE reaction, quickly switched off) to 100mg Zoloft plus 50mg Wellbutrin. It worked for a while, then I tapered off the Wellbutrin. Shortly after that, I went from 100mg to 50mg of Zoloft. This past week, my doc told me that I can experiment and start taking 25mg every other day for 1 month, and then if I feel alright then I can take 25mg daily from then on. Everyone is different. Don't be afraid of the side effects, sometimes it's worth it to push through them to get the results that you want. 25mg can work for you (and maybe it'll be much better for me, too!)

Hi. I'm in the same boat as you are and your not being a scary cat your just protecting your brain, body and well-being. So if it works, why change it then? I was prescribed same dose and it works enough for me to function better, so I'm not going higher. That's the problem I think. HCP always want to up the dose becuz sometimes it's needed, but not everytime. Everyone differs. Stick to your guns and stand by you! Best wishes :)

I am so happy to see this question. I was reluctant too and it’s been 8 days that I’ve been taking half of 50mg and my doctor told me to take half for 7 days and then the whole pill after that. I really think 25 mg is enough to take the edge off. I’m already very tired from this dose and I’m also a light weight

Mild anxiety/depression. Been on 25mg for almost 2 years - works like a charm - refused my doctors suggestion to go on to 50mg and have stayed on initial trial dosage. Keeps my George Constanza' moments at bay and sexual effect is actually enhanced. If it's not broke don't fix it.

I have been on different anxiety medications over the years. I was on Zoloft years ago and it seem to work but I quit taking it eventually. I went several years without taking any medications at all. After that I went back on Lexapro for several years and then started trying to find something that would work better. I eventually got off all of the meds because of the side effects. I’m now back on Zoloft and started on 25 mg which seem to have a good effect. The doctor upped me to 50 mg and now I’m having more panic than I had in the past. Would like to back down to 25 Mg but I’m wondering if I should just hold out and hope the side effects of 50 mg. subside. I am very sensitive to all medications and just wonder if 25 mg is my dose.

Hi, home!
It may be for you as every individual responds differently to medications at different doses. If you're satisfied with how you feel, then fine, but you seem to feel you could do even better. Try a slight increase to only 50mg for instance and see how it goes for you... it's you calling the shots but don't be afraid of a higher dose especially if a professional who knows you and your history recommends it. That's why they studied for all those years and are trained in psychopharmacology.
"The recommended initial dosage and maximum ZOLOFT dosage in patients with MDD, OCD, PD, PTSD, and SAD are displayed in Table 1 below. A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage.

For adults and pediatric patients, subsequent dosages may be increased in case of an inadequate response in 25 to 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day. Given the 24-hour elimination half-life of ZOLOFT, the recommended interval between dose changes is one week."

I have exactly the same issue. I take 25 ml the doctor who prescribed them suggests it may be a placebo effect but I know it helps. I am alight weight with all drugs. My GP tells me she has many patients who opt for 25 and feel better. I experimented 2 different occasions by upping it to 50 for a day and felt thick headed, my memory was poor and I was tired. Stick with 25 and know you have a lot of company.

I titrated myself fairly carefully with Zoloft (trying to find a dose that was therapeutic without having (male) sexual side effects), and found that 37.5 mg (25 + 1/2 * 25) was the minimal therapeutic dose for me (alternating days of 37.5 and 25 was not therapeutic). Higher doses had a little bit of additional benefit, but 37.5 was adequate for cutting out the severe lows. Alas, it still has sexual side effects (though not as bad as higher doses, like 100 or 150); adding Wellbutrin did not help. I'm in the process of starting on Vilazodone.

Every medication and dosage affects every individual patient differently. A 25mg daily dose is therapeutic if it works well for YOU.
"A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage.
For adults and pediatric patients, subsequent dosages may be increased in case of an inadequate response in 25 to 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day. Given the 24-hour elimination half-life of ZOLOFT, the recommended interval between dose changes is one week."

I took 25mg and I felt so much better. Now I'm on 50mg for 2 weeks and have had severe, intrusive, confusion thoughts/ideas... ANXIETY FROM HELL... severe eye spasms... and I can't type anymore because i cant remember.

I've been taking 25mg Zoloft for 15 years. Doctors tell me that 25mg is basically a placebo, but it works for me. No side effects. I've quit several times & I end up anxious and crying a lot. I'm also a lightweight. Small amounts of drugs tend to have a big effect with me.