I've been on zoloft 25 mg for two years and every time I see my doc he tries to up it telling me its not even a therapeutic dose. When I started the med I was feeling much worse anxiety/OCD then I am now so I feel it has helped. I'm sure I could feel better but I am anxious to up it, it was hard enough to take it at all since taking medications is a BIG hurdle for me. I do tend to be more of a light weight. Is anyone else on this low of a dose?
The thing you need to watch with Zoloft is whatever dose your on leave it alone my doctor had little to no exp. with these types of medication I started at 5 mg everytime I went back he would say did you notice a difference? I would say no and he would double it next thing I know it went from doing nothing to making me a zombie couldn't every find a correct dose took myself off of it and felt a lot better. One thing you have to watch and I've never seen anyone mention this or if was just me but marijuana and Zoloft adversely effect each other and things can get really bad hope this helps
The 25 mg of Zoloft is considered a child's dose. Nevertheless, while I was suffering suicidal anxiety, 25 mg helped me ENORMOUSLY. When my psychiatrist was emphatic that 50 mg was the therapeutic dose for adults, I complied. I began to "zone out." Every time I sat down I would just stare at the floor, or out the window. Everyone is different. 25 mg works for me, and keeps the anxious thoughts at bay. I listen to my body. I believe the majority of people when they say 50+ mg works for them. It just doesn't work for me.
25 mg worked for me as well. When my doctor urged me to increase the dosage to 50 mg, I felt detached and "zoned out" every chance I got. As long as 25 mg keeps me feeling "normal," I will continue on that dosage. This medicine works for me, and allows me to cope while I am under an enormous amount of stress. I wish you all the best, and pray it works for you, too, whatever the dosage that is right for YOU!
In 2012, I was put on a dose of 50mg Zoloft for around 9 months, then 25mg for 3 months before going off the drug. Within 3 months, severe anxiety returned so back I went on 50mg, then 25 mg and everything was fine. When the Doc tapered me down to 12.5 mg, symptoms returned.
Again back to 50 mg, then 25mg and then finally 12.5 mg for about 2 months when I did fine. I then made the mistake going off the drug and anxiety flared up again.
Right now I am on 25 mg but skipping the drug on alternate days so I am actually on about 12-15 mg and doing fine. I have established my own non drug self treatment regime.
I am convinced that certain treatments that are touted a cure all for anxiety are actually not helpful. I believe that mindfulness and certain thought challenging activities may exacerbate symptoms in certain individuals., especially OCD. I have about 1000+ hours of meditation practice so I do have some experience in that area.
Kind of light weight too. I'm on 25mg as well. I have been on it to counter OCD for a couple of momths. Sounds like the same dose is working for you. It seems to take the edge off intrusive thoughts. So far my only noticable side effects are weight gain and very low libido. So I'm tolerating it well. The sexual side effects bother me. I was told they can go away. 25mg is the lowest possible. Have you noticed any of the mentioned side effects?
My own experience (as an older male). Zoloft is the first antidepressant I've tried with a clearly useful effect for Persistent Depressive Disorder, and I'm about to change from 50 to 25 mg. I believe the effects are very dependent on the individual, so you just need to try for yourself.
50 mg Zoloft: significant effect (removal of severe emotional lows). Minor side effects (small reduction in sexual function).
100 mg Zoloft: also useful (additional focus/motivation). Significant sexual (erection and ejaculation) side effects (maybe retain 20% of full sexual function).
150 mg Zoloft: no obvious benefit, more reduction in sexual function (down to 5-10%).
I've reduced down to 50 mg and my mood is still fine, and sexual function is around 85%. So I'm about to try 25 mg. I probably won't report back, but this might be useful detail of one person's experience.
Every medication and dosage affects every individual patient differently. A 25mg daily dose is therapeutic if it works well for YOU.
"A dosage of 25 mg or 50 mg per day is the initial therapeutic dosage.
For adults and pediatric patients, subsequent dosages may be increased in case of an inadequate response in 25 to 50 mg per day increments once a week, depending on tolerability, up to a maximum of 200 mg per day. Given the 24-hour elimination half-life of ZOLOFT, the recommended interval between dose changes is one week."
I take 100 mg a day, but have taken every dose in increments of 25 mg for Zoloft between 25 mg and 200 mg that is possible. I've not liked going over 100 very much, but I occasionally have tinkered around in the 125-150 mg range, but I only find that to be helpful when I'm going through stressful life events/situations/living circumstances. I take it primarily for OCD, but also for panic disorder.
The two cons I really hate is some fatigue (especially without having stimulants), and the hormone affects to my prolactin and testosterone (ups prolactin and depletes testosterone), but having panic attacks all the time and chronically high cortisol it can actually help long-term (especially since I'm a college student) to control my panic attacks with exams and difficult lecture material.
For many years I was anti-psychotropics because I felt they were all wrecking my hormones and body, but there are certain people (like I deem myself) that do "better" with them regardless of the side effects (within reason).
Sometimes you really have to think hard and think what is going on in your life for the next say 1-5 years, what will be the most important things to treat at certain times, what combos/regimens work the best for you (if any), and dig deep to answer the tricky questions that only you can observe and decide upon.
I titrated myself fairly carefully with Zoloft (trying to find a dose that was therapeutic without having (male) sexual side effects), and found that 37.5 mg (25 + 1/2 * 25) was the minimal therapeutic dose for me (alternating days of 37.5 and 25 was not therapeutic). Higher doses had a little bit of additional benefit, but 37.5 was adequate for cutting out the severe lows. Alas, it still has sexual side effects (though not as bad as higher doses, like 100 or 150); adding Wellbutrin did not help. I'm in the process of starting on Vilazodone.
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