Hi, I started 25mg Zoloft about 2 months ago, after the first month I increased it to 37.5mg- I’m beyond exhausted. Just saw my doc who recommended going back down to 25mg as I’m very sensitive to ALL psych meds. I did see improvement on the 25mg. Has anyone else had this low dose help depression? I’ve tried Effexor, Pristiq, and Wellbutrin & Prozac which did NOTHING. In fact the Wellbutrin put me in the hospital. I’m at a loss & hoping lowering to the 25mg will eventually cause the fatigue to go away. I take around 5pm- this is the only time I can seem to remember.