Generic Name: tramadol (TRAM a dol)
Brand Names: ConZip, Rybix ODT, Ryzolt, Ultram
What is Ultram?
Ultram (tramadol) is a narcotic-like pain reliever.
Ultram is used to treat moderate to severe pain.
Ultram ER (extended-release) is for around-the-clock treatment of pain that is not controlled by other medicines.
Ultram may also be used for purposes not listed in this medication guide.
You should not take Ultram if you have used alcohol, sedatives, tranquilizers, or narcotic medications within the past few hours.
Ultram can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take Ultram in larger amounts, or for longer than prescribed. Do not crush or break an extended-release pill. Swallow it whole to avoid exposure to a potentially fatal dose.
Seizures (convulsions) have occurred in some people taking this medicine. Ultram may be more likely to cause a seizure if you have a history of seizures or head injury, a metabolic disorder, or if you are taking certain medicines such as antidepressants, muscle relaxers, narcotic, or medicine for nausea and vomiting
Tramadol may be habit-forming, even at regular doses. Take this medicine exactly as prescribed by your doctor. Never share the medicine with another person. MISUSE OF NARCOTIC PAIN MEDICATION CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Tell your doctor if you are pregnant. Ultram may cause life-threatening addiction and withdrawal symptoms in a newborn.
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with Ultram.
Do not crush the Ultram tablet. This medicine is for oral (by mouth) use only. Powder from a crushed tablet should not be inhaled or diluted with liquid and injected into the body. Using this medicine by inhalation or injection can cause life-threatening side effects, overdose, or death.
Before taking this medicine
You should not take Ultram if you are allergic to tramadol, or if you have:
severe asthma or breathing problems;
a blockage in your stomach or intestines;
if you have recently used alcohol, sedatives, tranquilizers, or narcotic medications.
Seizures have occurred in some people taking tramadol. Talk with your doctor about your seizure risk, which may be higher if you have:
a history of head injury, epilepsy or other seizure disorder;
a history of drug or alcohol addiction;
a metabolic disorder; or
if you are also using certain medicines to treat migraine headaches, muscle spasms, depression, mental illness, or nausea and vomiting.
To make sure Ultram is safe for you, tell your doctor if you have:
liver or kidney disease;
a stomach disorder; or
a history of drug abuse, alcohol addiction, mental illness, or suicide attempt.
Ultram is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.
Tramadol may be habit forming and should be used only by the person it was prescribed for. Never share Ultram with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away Ultram to any other person is against the law.
FDA pregnancy category C. It is not known whether Ultram will harm an unborn baby. Ultram may cause breathing problems, behavior changes, or life-threatening addiction and withdrawal symptoms in your newborn if you use the medication during pregnancy. Tell your doctor if you are pregnant.
See also: Pregnancy and breastfeeding warnings (in more detail)
Tramadol can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are taking Ultram.
Do not give this medication to anyone younger than 16 years old without the advice of a doctor. Ultram ER should not be given to anyone younger than 18 years old.
How should I take Ultram?
Take Ultram exactly as prescribed. Follow all directions on your prescription label. Ultram can slow or stop your breathing, especially when you start using this medicine or whenever your dose is changed. Never take Ultram in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Stop taking all other around-the-clock narcotic pain medications when you start taking Ultram.
Ultram can be taken with or without food, but take it the same way each time.
Do not crush or break an extended release Ultram ER tablet. Swallow the tablet whole to avoid exposure to a potentially fatal dose.
Never crush or break a Ultram tablet to inhale the powder or mix it into a liquid to inject the drug into your vein. This practice has resulted in death with the misuse of tramadol and similar prescription drugs.
If you use the Ultram ER extended-release tablet, the tablet shell may pass into your stools (bowel movements). This is normal and does not mean that you are not receiving enough of the medicine.
Do not stop using Ultram suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using Ultram.
Store at room temperature away from moisture and heat.
Keep track of the amount of medicine used from each new bottle. Tramadol is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. A tramadol overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, cold and clammy skin, and fainting.
What should I avoid?
Do not drink alcohol. Dangerous side effects or death can occur when alcohol is combined with tramadol. Check your food and medicine labels to be sure these products do not contain alcohol.
Ultram may impair your thinking or reactions. Avoid driving or operating machinery until you know how this medicine will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Ultram side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Ultram: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
weak or shallow breathing;
high levels of serotonin in the body--agitation, hallucinations, fever, fast heart rate, overactive reflexes, nausea, vomiting, diarrhea, loss of coordination, fainting; or
severe skin reaction--fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common Ultram side effects may include:
headache, dizziness, drowsiness, tired feeling;
constipation, diarrhea, nausea, vomiting, stomach pain; or
feeling nervous or anxious.
itching, sweating, flushing (warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Ultram?
Taking this medicine with other drugs that make you sleepy or slow your breathing can cause dangerous or life-threatening side effects. Ask your doctor before taking Ultram with a sleeping pill, narcotic pain medicine, muscle relaxer, or medicine for anxiety, depression, or seizures.
Many drugs can interact with tramadol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Compare with other treatments for:
Where can I get more information?
- Your pharmacist can provide more information about Ultram.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Ultram only for the indication prescribed.
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