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Hydrochlorothiazide / moexipril Side Effects

Medically reviewed by Drugs.com. Last updated on Feb 4, 2024.

Applies to hydrochlorothiazide / moexipril: oral tablet.

Warning

  • Do not take if you are pregnant. Use during pregnancy may cause birth defects or loss of the unborn baby. If you get pregnant or plan on getting pregnant while taking this drug, call your doctor right away.

Serious side effects

WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:

Other side effects

All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:

These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at 1-800-332-1088. You may also report side effects at https://www.fda.gov/medwatch.

For Healthcare Professionals

Applies to hydrochlorothiazide/moexipril: oral tablet.

General

The most common adverse reactions were cough, dizziness, and fatigue.[Ref]

Other

Common (1% to 10%): Fatigue, pain, flu syndrome, chest pain, peripheral edema, fever

Hydrochlorothiazide:

Frequency not reported: Weakness[Ref]

Respiratory

Common (1% to 10%): Cough, upper respiratory infection, rhinitis, sinusitis, bronchitis

Hydrochlorothiazide:

Frequency not reported: Respiratory distress, pneumonitis, pulmonary edema[Ref]

Nervous system

Common (1% to 10%): Dizziness, headache, vertigo, hypertonia

Hydrochlorothiazide:

Frequency not reported: Vertigo, dizziness, headache, paresthesia[Ref]

Gastrointestinal

Common (1% to 10%): Diarrhea, abdominal pain, dyspepsia, nausea

Hydrochlorothiazide:

Frequency not reported: Pancreatitis, sialadenitis, vomiting, diarrhea, cramping, nausea, gastric irritation, constipation[Ref]

Metabolic

Common (1% to 10%): Hyperuricemia, hyperglycemia, hypokalemia

Hydrochlorothiazide:

Frequency not reported: Anorexia, hyperglycemia, hyperuricemia[Ref]

Genitourinary

Common (1% to 10%): Urinary tract infection, impotence, pyuria

Hydrochlorothiazide:

Frequency not reported: Glycosuria[Ref]

Dermatologic

Common (1% to 10%): Rash

Hydrochlorothiazide:

Frequency not reported: Stevens-Johnson syndrome, purpura, urticaria, rash, photosensitivity[Ref]

Cardiovascular

Common (1% to 10%): Abnormal ECG

Hydrochlorothiazide:

Frequency not reported: Orthostatic hypotension, necrotizing angiitis[Ref]

Hepatic

Common (1% to 10%): Serum glutamic pyruvic transaminase (SGPT) increased

Hydrochlorothiazide:

Frequency not reported: Intrahepatic cholestatic jaundice[Ref]

Musculoskeletal

Common (1% to 10%): Back pain

Hydrochlorothiazide:

Frequency not reported: Muscle spasm[Ref]

Immunologic

Common (1% to 10%): Infection[Ref]

Hematologic

Hydrochlorothiazide:

Frequency not reported: Aplastic anemia, agranulocytosis, leukopenia, thrombocytopenia[Ref]

Ocular

Hydrochlorothiazide:

Frequency not reported: Transient blurred vision, xanthopsia[Ref]

Renal

Moexipril:

Frequency not reported: BUN increased, serum creatinine increased[Ref]

Psychiatric

Hydrochlorothiazide:

Frequency not reported: Restlessness[Ref]

References

1. Product Information. Uniretic (hydrochlorothiazide-moexipril). Schwarz Pharma. 2001;PROD.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.