Naratriptan Dosage

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Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Migraine

Acute migraine with or without aura in adults: (Note: The drug should not be administered to patients with hemiplegic or basilar migraine.)
1 to 2.5 mg orally with fluid. If the headache returns or if the patient has only a partial response, the dose may be repeated once after 4 hours. The safety of treating more than four headaches in a 30 day period has not been established.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

No adjustments recommended

Precautions

Naratriptan is contraindicated in patients with severe liver dysfunction. The manufacturer does not recommend the use of naratriptan in patients with a creatinine clearance below 15 mL/min.

Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).

Dialysis

Data not available

Other Comments

There have been rare reports where patients received serotonin agonists for severe headaches that were subsequently shown to have been secondary to an evolving neurologic lesion. For a given attack, if a patient has no response to the first dose of naratriptan, the diagnosis of migraine should be reconsidered before the administration of a second dose.

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