Naratriptan Pregnancy and Breastfeeding Warnings

Naratriptan is also known as: Amerge

Naratriptan Pregnancy Warnings

Naratriptan has been assigned to pregnancy category C by the FDA. Animal tests have reported developmental toxicity (embryolethality, fetal abnormalities, pup mortality, and offspring growth retardation), dose-related increases in embryonic death, and fetal structural variations (incomplete/irregular ossification of skull bones, sternebrae, and ribs). High doses in animals have been reported to have lead to fused sternebrae, increased incidences of embryonic death, and fetal variations (major blood vessel variations, supernumerary ribs, and incomplete skeletal ossification). Treatment in animals during late gestation and lactation has been reported to have lead to offspring behavioral impairment (tremors), and decreased offspring viability and growth. There are no controlled data in human pregnancy. Naratriptan should only be given during pregnancy when benefit outweighs risk.

Naratriptan Breastfeeding Warnings

There are no data on the excretion of naratriptan into human milk.

The manufacturer has reported that naratriptan related material is excreted in the milk of rats.

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