Flurazepam Dosage

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Usual Adult Dose for:

Usual Geriatric Dose for:

Usual Pediatric Dose for:

Additional dosage information:

Usual Adult Dose for Insomnia

30 mg orally before retiring.
In some patients, 15 mg may suffice.

Usual Geriatric Dose for Insomnia

15 mg orally before retiring.

Usual Pediatric Dose for Insomnia

Less than 15 years: No dose has been established. Use is not recommended by the manufacturer.

Greater than 15 years: 15 mg orally before retiring.

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Dose Adjustments

For debilitated patients: 15 mg orally before retiring.

Precautions

Use with caution in patients with hepatic dysfunction.

Flurazepam should not be discontinued abruptly in patients who have received the medication for long periods. Abrupt discontinuation may result in symptoms of withdrawal.

Because this benzodiazepine hypnotic has an extremely long half-life in elderly patients producing prolonged sedation and increasing the incidence of falls and fractures, flurazepam meets the Beers criteria as a medication that is potentially inappropriate for use in older adults. Medium- or short-acting benzodiazepines are preferable for use in elderly patients. A large prospective cohort study found that among benzodiazepines and independent of half-life, higher doses of flurazepam, chlordiazepoxide, and oxazepam are associated with the greatest risk of injury (e.g., fall- related fracture or laceration) in the elderly. The authors suggest that these benzodiazepines should be avoided in the elderly, particularly at higher doses.

Dialysis

Data not available

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