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Pregabalin for Pain User Reviews (Page 3)

Brand names: Lyrica, Lyrica CR

Pregabalin has an average rating of 6.6 out of 10 from a total of 162 reviews for the off-label treatment of Pain. 57% of reviewers reported a positive experience, while 26% reported a negative experience.

Reviews for Pregabalin

  • jramb...
  • Taken for 2 to 5 years
  • October 13, 2019

"Was on Lyrica for three years for pain from due to degenerate discs in my back and very bad sciatica from bulging discs. Works great for pain but around the third year I noticed increased joint pain in knees and hips that continued to get worse. I decided to go off lyrica and while the first week was pretty bad for pain since I've been off my joint pain has almost gone away. No more knee or hip pain. Not sure why or how but the change is incredible."

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  • Spots
  • Taken for less than 1 month
  • June 22, 2020

"I had a thoracic spinal cord injury that left my legs numb and resulted in musculoskeletal pain as a result of poor body mechanics. I took Gabapentin for 6 months but I developed clinical depression and suicidal ideation (I never had a mental health disease prior). Switched to lyrica. The depression left but my legs felt like they were shot up with novocaine and I could not feel my feet @only 50mg a day. Fell three times in the first week. No thanks."

2 / 10
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  • janze...
  • April 12, 2011

Lyrica (pregabalin) "Started on 75mg twice daily, noticed some effect, just a tease or a promise. Upped it to 150mg twice daily and yes, it definitely works to eliminate "one level of pain", while leaving some "levels of pain" still there. I do feel side effects of feeling calm while having more motivation for projects, some slight feeling of alcohol-like impairment (not so much after less than a week of 300mg/day). I also occasionally use oral cannabis and the Lyrica potentiates it quite a bit. I'm feeling very positive about this medicine, even though it doesn't get at all levels of my pain, I like what it does do for me."

8 / 10
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Frequently asked questions

  • Anonymous
  • August 14, 2010

Lyrica (pregabalin) "Lyrica has been a life saver for me. Prior to being prescribed Lyrica, I was living with terrible burning pain because of vulvodynia. Lyrica provided me with the relief I did not get from any other drugs. I can now enjoy life with little to no pain. I am so thankful that I was prescribed Lyrica."

9 / 10
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  • unreg...
  • August 5, 2008

Lyrica (pregabalin) "I suffer from severe peripheral neuropathy. It is unusual in the sense that it is not diabetes caused, but is apparently idiopathic and hereditary. I have excellent relief from Lyrica with few side effects. I find myself nodding out occasionally at my computer or watching TV. I exercise more, drink more coffee, and allow more time for sleep. The more I take, the greater the relief. I take 400mg per day. "

8 / 10
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Are you taking this medicine?

  • Anonymous
  • July 29, 2010

Lyrica (pregabalin) "I took Lyrica for about 2 years and loved it. It helped my pain so much. I suffer with back pain and leg pain. I went from Topamax to Lyrica and it was a big difference. I gained weight about 20lbs, but my problem was my insurance would not cover this medicine and it doesn't have a generic. So I was having to pay almost $360.00/month for 60 pills. Couldn't afford it so I've had to go back to Topamax. Now I've lost almost 30 pounds and don't like it as much as Lyrica and it has more side effects. So stay with Lyrica if you can - it's a great medicine."

9 / 10
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  • Bless...
  • June 12, 2009

Lyrica (pregabalin) "I have been suffering from severe pudendal nerve damage pain and fibromyalgia for over 12 years. Vicodin, Percocet, Duragesic, Oxycontin, injections, you name it. Lyrica 75mg 2-3 x day has made the biggest difference in my life and pain in over 12 years. I can walk without a cane and I feel like doing things. There was some initial weight gain, but that seems to have leveled off. I've been amazed and very pleased."

10 / 10
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More FAQ

  • Plantar...
  • Taken for less than 1 month
  • December 3, 2022

"I didn't like this big time. It didn't help with pain at all, but made me feel like you know when your hand falls asleep and you kind of feel it but it feels numb at the same time? So, this is how I felt. I barely was able to get up this morning. Now I am trying to get out of this condition and wonder how long this pill works. Also, I feel nauseated. I already had tea, and breakfast , about to have coffee. I feel like a jellyfish on the beach. I am going to call the pharmacist and ask how long this affects the body, because I want to feel normal again. And as for pain, big fat 0. No help at all."

1 / 10
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  • Martha
  • December 11, 2020

"I have been on pregabalin for three weeks now we (Doc and I) are slowly increasing the dose. I have AS and have awful pain in the sciatic nerve down my hip and leg and into my knee plus the pain in my spine from shoulder to hip unbearable in the base of my spine and electric shocks if I moved the wrong way the whole deal. I could hardly walk and was bent over in pain. Pregabalin is really helping the pain, it has not disappeared but it’s becoming more bearable as we increase the dose. The only side effects I have had was a little dizziness in the first day or two of taking it and feeling tired, but this wore of about day three to four. I use a low dose of tramadol with it at night and I haven’t slept so well in years. Well worth trying and persevering over the first few days as your body gets used to it."

8 / 10
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  • Anonymous
  • October 6, 2009

Lyrica (pregabalin) "I have Degenerative disc disease and 4 herniated disks. I have been down the road of dependence on Oxycontin and Duragesic. Those medicines worked great, however, they do not hold up as they claim. My doctor put me on Lyrica at 300mg a day and what a difference it has made! My mobility is much better as well as my mental outlook on life. This medicine seems to do the job. I like it and recommend it."

10 / 10
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  • Wound...
  • August 24, 2008

Lyrica (pregabalin) "I think its great. I was skeptical when my doctor prescribed it to me, as it is so unfamiliar to me, especially as a pain medicine. I thought I had tried everything. It is for chronic back pain due to a severe spinal injury I suffered two years and 3 surgeries ago. My pain has been steadily decreasing since I started taking this medication four days ago. Thank Science."

7 / 10
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  • GollyI
  • Taken for 1 to 2 years
  • August 4, 2020

"I have been taking pregablin for over a year now to treat vulvadynia and my pain as gone but can still have the burning sensation Side effects are not good weight gain memory loss tiredness and feeling not well when I wake up.Would love to come of them but I fear my intense pain would reoccur"

6 / 10
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  • Groszy
  • Taken for less than 1 month
  • November 9, 2019

"My condtion is generalized overall severe body stiffness and pain when moving. Took half dose pregabalin . One capsule at night. By 3rd night I woke up with stinging, huge weeping, red patches on my neck. Still have the rash bit stinging snd weeping less. I am completely drugged out. Woozy. Not sleepy. Completely hung over over 12 hours later."

1 / 10
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  • mdpra...
  • February 18, 2011

Lyrica (pregabalin) "Finally, a medicine prescribed by my psychiatrist that is non narcotic and actually works. Due to a severe auto accident fifteen years ago, I am now 40 yrs old, and having suffered a closed head injury, fractured pelvis, 4 fractured ribs and tailbone fracture. I have suffered with chronic pain mostly my adult like. I have undergone nearly every pain management regime one can think of: Epid nerve blocks, rhizotomy, physical therapies and of course every narcotic medicine that was available. Yet within just a few months, and after all these years, Doctor and I have finally found a medication regimen that truly works! Lyrica 75 2x a day and MS 60mg 2x daily. And since starting Lyrica, my acute pain episodes are less frequent."

5 / 10
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  • Sair
  • Taken for less than 1 month
  • September 16, 2019

"I had a hip replacement 10 weeks ago I'm 46 Hip feels fantastic but my calf muscles and shins are aching constantly and left foot was numb after surgery. (Nerve damage?) Since week 8 it was getting worse so I was prescribed pregabalin to try... within 1 hour I have got relief hopefully it works as I swim 2 times a week and was back nursing at week 6 Fingers crossed "

10 / 10
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  • trucklt
  • February 22, 2011

Lyrica (pregabalin) "I've had back pain from degenerative discs since 1998. After all the usual treatments such as chiro, physical therapy, injections, etc., I had a L4/L5 fusion on 02/09. It helped a little, but still had substantial back pain requiring Ultracet 3x per day and Lortabs when pain peaked. Have been on Lyrica 75mg 3x per day for past 11 days. Really reduced the pain the first few days, but pain came back a bit. Still, the Lyrica is helping and I've not had to take the Lortabs since starting Lyrica. I'm going to stick with Lyrica for a few more weeks before deciding to try more injections or other medicines."

8 / 10
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  • lymes
  • March 25, 2011

Lyrica (pregabalin) "I have spondylosis of the whole spine and lumbar degeneration. I've been on Lyrica for a few months 75mg 3 times a day. It helps my range of motion at my knees, helps to walk up stairs, and also no pain when push for bowl movement."

4 / 10
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  • 33...
  • December 12, 2008

Lyrica (pregabalin) "I JUST started using this drug 3 days ago. I have been suffering with horrible pain from a herniated disc over the past 2 months. Tried hydrocortisone shots in my back and the pain went away for 3-4 days. I've been on vicodin and skelaxin as well as Aleve twice a day. I've had to take my vicodin every 4 hours instead of every 6 hours because the pain has been so bad. Just in the last 48 hours, I've noticed such a difference with Lyrica. I keep waiting for the pain to be there, but it is NOT. I'm still titrating my way up on the dosage, but in another day or two, my maximum dose will be 50 mg 3 times a day. Currently, I'm taking 50 mg 2 times a day. It really works."

10 / 10
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  • BCano
  • Taken for 2 to 5 years
  • October 10, 2019

"On Lyrica 100mg for about 3 years, controls my lower abdomen pain--related/referred to back pain. I have been on the generic Pregabalin 100 mg for 8 days and pain started to come back. Took 50 mg of the real stuff and pain went away until about 24 hours later. Will be experimenting with it for the next few days to see what happens-but I'm concerned. I was expecting it to work since I have used generic drugs in the past and noticed no difference. Its a big cost savings for me: $10 vs $50/month--but I'll pay extra to have no pain. I am adding to this to see if there are more than 2 of us with this problem."

2 / 10
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  • Anonymous
  • September 12, 2009

Lyrica (pregabalin) "I have severe pain in my legs and chronic fatigue. Been going to doctors for over a year, have had 3 MRI's, and gallons of blood taken and tested. Yet nobody knows the source of these symptoms. Due for a muscle biopsy soon. While taking tramadol and hydrocodone had great results for energy and pain, I became dependent. I was prescribed Lyrica 50mg about 2 months ago and felt a little relief. Doctor raised the dosage and now I take 150mg 3 times a day and the results are amazing. I'm alert, energetic, and pain free. Have a little dizziness now and then, but this medicine is great."

8 / 10
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  • I...
  • Taken for less than 1 month
  • March 27, 2021

"I have had back pain 24/7 for 3 years. Tried everything you can image. Out of all the medications and other treatments, pregabalin helps the most. After a week my spine, nerves and muscles felt less pain. Kind of feels numb now? My chronic restless legs have calmed by 80%. My fibromyalgia is better 60%. Not sure yet if it is helping with anxiety as I take lorazapam. Today I'm trying to drop the lorazapam. See how it goes. It does cause constipation so I have another pill for that. Overall, I am having a positive result with pregabalin"

8 / 10
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  • debbie
  • September 12, 2009

Lyrica (pregabalin) "I have a bad lumbar disc L5-S1 in my low back which needs to be removed. I'm taking Lycria because it helps keep the pain from going down my leg. Lyrica works great. If it wasn't for Lyrica I wouldn't be walking."

10 / 10
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  • mamac
  • May 20, 2008

Lyrica (pregabalin) "My doctor prescribed this for me when I was dealing with pain from a fractured sternum. After dealing with the pain for over a year we tried this. Fantastic results. Required only 3 weeks of treatment and the pain resolved."

10 / 10
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  • Random...
  • Taken for 1 to 6 months
  • October 25, 2020

"I take pregabalin at bedtime for fibromyalgia, interstitial cystitis, vulvodynia and after-effects of artificial disc replacement which include restlessness in my right arm and right leg (my neck was cut on my right side), pain in my right leg, right hip pain as well as pain in both shoulders, especially bursitis in one shoulder. Pregabalin is no cure but it has made my bed feel more comfortable and improved my sleep. I'm a wuss with side effects so I started at the lowest dose of 25 mg the first night, then 50 mg the next two weeks and 75 mg the last four weeks. I tried taking a dose in the morning but it zapped me so I just keep moving during the day. The side effects of headaches, thirst and constipation have improved with time. I tried gabapentin multiple times and never could get past the awful side effects even at a low dose."

9 / 10
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  • gmbas...
  • July 23, 2009

Lyrica (pregabalin) "I have had a fusion of L4 and L5 in 2004 was doing fine until last year when I began to have pain in my low back and right leg accompanied with numbness and tingling down the leg. I also managed to severely rupture a few discs in my neck while stretching of all things. Was misdiagnosed by the surgeon who only fixed one of the ruptures with a fusion of C7. Off course this still left me with pain and numbness from my neck down both arms. About a month or so ago I switched to a spine and pain management doctor and he put me on the Lyrica (75mg 3x daily) and a Duragesic patch. These two drugs have worked wonders for my pain and Quality of life. The only side effect is that my short term memory is a little sketchy and my mind doesn't want to shut down."

9 / 10
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Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.