Tobramycin/
Dexamethasone Drops

Tobramycin/Dexamethasone Drops is used for:

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Treating eye infections and associated symptoms, including redness, irritation, and discomfort.

Tobramycin/Dexamethasone Drops is an antibiotic (tobramycin) and a corticosteroid (dexamethasone) combination. The antibiotic works by slowing the growth of, or killing, sensitive bacteria in the eye. The corticosteroid works by reducing inflammatory reactions.

Do NOT use Tobramycin/Dexamethasone Drops if:

• you are allergic to any ingredient in Tobramycin/Dexamethasone Drops
• you have tuberculosis, fungal, or viral (eg, herpes simplex, chickenpox, shingles) eye infection

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tobramycin/Dexamethasone Drops:

Some medical conditions may interact with Tobramycin/Dexamethasone Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, plan to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have thinning of the cornea or the white part of the eye
• if you have diabetes

Some MEDICINES MAY INTERACT with Tobramycin/Dexamethasone Drops. Because little, if any, of Tobramycin/Dexamethasone Drops is absorbed into the blood, the risk of interacting with another medicine is low.

Ask your health care provider if Tobramycin/Dexamethasone Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tobramycin/Dexamethasone Drops:

Use Tobramycin/Dexamethasone Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tobramycin/Dexamethasone Drops is only for the eye. Do not get it in your nose or mouth.
• Shake well before each use.
• To use Tobramycin/Dexamethasone Drops in the eye, first, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
• To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
• Do not wear contact lenses while you are using Tobramycin/Dexamethasone Drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
• Using Tobramycin/Dexamethasone Drops at the same time each day will help you to remember to use it.
• To clear up your infection completely, use Tobramycin/Dexamethasone Drops for the full course of treatment. Keep using it even if you feel better in a few days.
• If you miss a dose of Tobramycin/Dexamethasone Drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Tobramycin/Dexamethasone Drops.

Important safety information:

• Tobramycin/Dexamethasone Drops may cause blurred vision. Use Tobramycin/Dexamethasone Drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
• If your symptoms do not improve within a few days or if they get worse, check with your doctor.
• Be sure to use Tobramycin/Dexamethasone Drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
• Long-term or repeated use of Tobramycin/Dexamethasone Drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
• Do not use Tobramycin/Dexamethasone Drops for future eye problems unless directed by your doctor.
• Tobramycin/Dexamethasone Drops should not be used in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tobramycin/Dexamethasone Drops while you are pregnant. It is not known if Tobramycin/Dexamethasone Drops is found in breast milk. If you are or will be breast-feeding while you use Tobramycin/Dexamethasone Drops, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Tobramycin/Dexamethasone Drops:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Burning, or stinging when you first put the medicine in your eye; delayed wound healing.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching and swelling of the eyelid; redness or swelling of the eye; second infection; severe eye pain; vision loss.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include flushing; increased tearing; lid itching; redness, swelling; and spots or lesions on the surface of the cornea.

Store Tobramycin/Dexamethasone Drops between 46 and to 80 degrees F (8 and 27 degrees C). Store upright in the original container, tightly closed, and away from heat, moisture, and light. Do not store in the bathroom. Keep Tobramycin/Dexamethasone Drops out of the reach of children and away from pets.

General information:

• If you have any questions about Tobramycin/Dexamethasone Drops, please talk with your doctor, pharmacist, or other health care provider.
• Tobramycin/Dexamethasone Drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Tobramycin/Dexamethasone Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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