Generic Name: tobramycin/dexamethasone (TOE-bra-MYE-sin/DEX-a-METH-a-sone)
Brand Name: TobraDex ST
Tobramycin/dexamethasone drops is used for:
Treating certain types of eye inflammation where a bacterial infection exists or may develop.
Tobramycin/dexamethasone drops is an antibiotic (tobramycin) and a corticosteroid (dexamethasone) combination. The antibiotic works by preventing the growth of, or killing, sensitive bacteria in the eye. The corticosteroid works by reducing inflammatory reactions.
Do NOT use tobramycin/dexamethasone drops if:
- you are allergic to any ingredient in tobramycin/dexamethasone drops
- you have a mycobacterial, fungal, or viral (eg, herpes simplex, vaccinia, chickenpox) eye infection
Contact your doctor or health care provider right away if any of these apply to you.
Before using tobramycin/dexamethasone drops:
Some medical conditions may interact with tobramycin/dexamethasone drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, plan to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, especially to other aminoglycosides (eg, gentamicin); foods; or other substances
- if you have thinning of the cornea (the surface of the eye), or oozing from the eye
- if you have diabetes, glaucoma or increased eye pressure, or have recently had cataract surgery
- if you have a history of viral eye infections (eg, herpes simplex)
- if you are using another form of aminoglycoside antibiotic (eg, intravenous)
Some MEDICINES MAY INTERACT with tobramycin/dexamethasone drops. Because little, if any, of tobramycin/dexamethasone drops is absorbed into the blood, the risk of interacting with another medicine is low.
Ask your health care provider if tobramycin/dexamethasone drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use tobramycin/dexamethasone drops:
Use tobramycin/dexamethasone drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Tobramycin/dexamethasone drops is only for the eye. Do not get it in your nose or mouth. Do not inject it into the eye.
- Shake well before each use.
- To use tobramycin/dexamethasone drops in the eye, first wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eyelid for 1 to 2 minutes. Do not blink. Remove excess medicine around your eye with a clean, dry tissue, being careful not to touch your eye. Wash your hands to remove any medicine that may be on them.
- To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including the eye. Keep the container tightly closed.
- Do not wear contact lenses while you are using tobramycin/dexamethasone drops. Take care of your contact lenses as directed by the manufacturer. Check with your doctor before you use them.
- Using tobramycin/dexamethasone drops at the same time each day will help you to remember to use it.
- To clear up your infection completely, use tobramycin/dexamethasone drops for the full course of treatment. Keep using it even if you feel better in a few days.
- If you miss a dose of tobramycin/dexamethasone drops, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.
Ask your health care provider any questions you may have about how to use tobramycin/dexamethasone drops.
Important safety information:
- Tobramycin/dexamethasone drops may cause blurred vision. Use tobramycin/dexamethasone drops with caution. Do not drive or perform other possibly unsafe tasks if you cannot see clearly.
- If your symptoms do not improve within 2 days or if they get worse, check with your doctor.
- Check with your doctor if you have an eye wound or irritation that does not heal.
- Prolonged use of tobramycin/dexamethasone drops (eg, 10 days or longer) may increase the risk of glaucoma. Your doctor may monitor the pressure in your eye(s) while you use tobramycin/dexamethasone drops. Discuss any questions or concerns with your doctor.
- Be sure to use tobramycin/dexamethasone drops for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
- Long-term or repeated use of tobramycin/dexamethasone drops may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
- Do not use tobramycin/dexamethasone drops for future eye problems unless directed by your doctor.
- Tobramycin/dexamethasone drops should be used with extreme caution in CHILDREN younger than 2 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using tobramycin/dexamethasone drops while you are pregnant. It is not known if tobramycin/dexamethasone drops is found in breast milk after topical use. If you are or will be breast-feeding while you use tobramycin/dexamethasone drops, check with your doctor. Discuss any possible risks to your baby.
Possible side effects of tobramycin/dexamethasone drops:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Burning or stinging when you first put the medicine in your eye.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); changes in vision; itching or swelling of the eyelid; new or worsening eye pain, redness, swelling, or irritation; vision loss.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include increased tearing; lid itching; redness or swelling of the eye.Proper storage of tobramycin/dexamethasone drops:
Store tobramycin/dexamethasone drops between 36 and 77 degrees F (2 and 25 degrees C). Store upright in the original container, tightly closed, and away from heat, moisture, and light. Do not store in the bathroom. Keep tobramycin/dexamethasone drops out of the reach of children and away from pets.
- If you have any questions about tobramycin/dexamethasone drops, please talk with your doctor, pharmacist, or other health care provider.
- Tobramycin/dexamethasone drops is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take tobramycin/dexamethasone drops or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about tobramycin/dexamethasone drops. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to tobramycin/dexamethasone drops. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using tobramycin/dexamethasone drops.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.