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Metoprolol tartrate tablets

Generic Name: metoprolol tartrate (MET-oh-PROE-lol TAR-trate)
Brand Name: Lopressor

Do not suddenly stop taking metoprolol tartrate tablets. Sharp chest pain, irregular heartbeat, and sometimes heart attack may occur if you suddenly stop metoprolol tartrate tablets. The risk may be greater if you have certain types of heart disease. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. This should be done even if you only take metoprolol tartrate tablets for high blood pressure. Heart disease is common and you may not know you have it. Limit physical activity while you are lowering your dose. If new or worsened chest pain or other heart problems occur, contact your doctor right away. You may need to start taking metoprolol tartrate tablets again.

Tell your doctor or dentist that you take metoprolol tartrate tablets before you receive any medical or dental care, emergency care, or surgery.

Tell your doctor if you have a history of diabetes or if you take medicine to lower your blood sugar (eg, glyburide, insulin). Metoprolol tartrate tablets may hide signs of low blood sugar, such as fast heartbeat. Be sure to watch for other signs of low blood sugar (eg, anxiety, chills, dizziness, drowsiness, fainting, headache, tremor, unusual sweating, vision changes, weakness). Tell your doctor right away if these effects occur.

Metoprolol tartrate tablets should not usually be used by patients who have a history of certain lung or breathing problems (eg, asthma) or who have a certain type of adrenal gland tumor (pheochromocytoma). It may worsen these conditions. Tell your doctor if you have a history of breathing problems or adrenal gland tumors. If you have these conditions and must take metoprolol tartrate tablets, your doctor may need to adjust your dose or prescribe additional medicine to reduce the risk of side effects. Check with your doctor for more information.

Tell your doctor if you have a history of overactive thyroid. Metoprolol tartrate tablets may hide symptoms of overactive thyroid (eg, fast heartbeat). Do not suddenly stop taking metoprolol tartrate tablets; suddenly stopping metoprolol tartrate tablets could worsen your condition. Your doctor should slowly lower your dose over several weeks if you need to stop taking it. Check with your doctor for more information.


Metoprolol tartrate tablets is used for:

Treating high blood pressure. It may be used alone or with other medicines. It is also used for the long-term treatment of chest pain (angina) and for reducing the risk of death because of heart problems in certain patients who have had a heart attack. It may also be used for other conditions as determined by your doctor.

Metoprolol tartrate tablets is a beta-adrenergic blocking agent (beta-blocker). It works by reducing the amount of work the heart has to do (reduces chest pain) and the amount of blood the heart pumps out (lowers high blood pressure). It is also used to stabilize the heart rhythm in conditions in which the heart is beating too fast or in an irregular rhythm.

Do NOT use metoprolol tartrate tablets if:

  • you are allergic to any ingredient in metoprolol tartrate tablets or to another beta-blocker (eg, propranolol)
  • you have a very slow heart rate (eg, bradycardia), certain types of irregular heartbeat (eg, atrioventricular [AV] block, sick sinus syndrome), moderate to severe heart failure, very low systolic blood pressure (less than 100 mm Hg), or severe blood circulation problems
  • you are taking mibefradil

Contact your doctor or health care provider right away if any of these apply to you.

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Before using metoprolol tartrate tablets:

Some medical conditions may interact with metoprolol tartrate tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have an adrenal gland tumor (pheochromocytoma), an overactive thyroid, or are scheduled to have surgery
  • if you have low blood pressure or a history of heart attack, slow or irregular heartbeat, heart failure, or other heart problems; chest pain or angina; blood circulation problems; or liver problems
  • if you have diabetes or low blood sugar, chronic obstructive pulmonary disease (COPD), bronchitis, breathing problems, or a history of asthma

Some MEDICINES MAY INTERACT with metoprolol tartrate tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Abiraterone, alfuzosin, amiodarone, betanidine, bupropion, cimetidine, clomipramine, desipramine, digoxin, diltiazem, diphenhydramine, duloxetine, ergotamine, flecainide, certain HIV protease inhibitors (eg, ritonavir), guanethidine, haloperidol, hydralazine, hydroxychloroquine, ketanserin, mefloquine, mibefradil, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), phenothiazines (eg, thioridazine), prazosin, propafenone, propylthiouracil, quinazolines (eg, alfuzosin), quinidine, reserpine, certain selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, paroxetine), terbinafine, or verapamil because serious side effects, such as very slow heart rate, very low blood pressure, fainting, severe dizziness, or light-headedness when standing, may occur
  • Clonidine because stopping it or metoprolol tartrate tablets suddenly can lead to a rapid increase in blood pressure
  • Indomethacin or rifamycins (eg, rifampin) because they may decrease metoprolol tartrate tablets's effectiveness
  • Fingolimod, hydralazine, or lidocaine because the risk of their side effects may be increased by metoprolol tartrate tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if metoprolol tartrate tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use metoprolol tartrate tablets:

Use metoprolol tartrate tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take metoprolol tartrate tablets by mouth with food or immediately following a meal at the same time each day.
  • Swallow metoprolol tartrate tablets whole with a full glass of water. Do not chew before swallowing.
  • Continue to take metoprolol tartrate tablets even if you feel well. Do not miss any doses.
  • If you miss a dose of metoprolol tartrate tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use metoprolol tartrate tablets.

Important safety information:

  • Metoprolol tartrate tablets may cause drowsiness, dizziness, or light-headedness. These effects may be worse if you take it with alcohol or certain medicines. Use metoprolol tartrate tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Metoprolol tartrate tablets may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
  • Patients who take medicine for high blood pressure often feel tired or run down for a few weeks after starting treatment. Be sure to take your medicine even if you may not feel "normal." Tell your doctor if you develop any new symptoms.
  • Do not suddenly stop taking metoprolol tartrate tablets without first consulting your doctor. If your doctor decides you should no longer use metoprolol tartrate tablets, you will need to stop metoprolol tartrate tablets gradually according to your doctor's instructions.
  • If your doctor has instructed you to check your blood pressure and heart rate regularly, be sure to do so.
  • Do not take any medicines used to treat colds or congestion without first talking with your doctor or pharmacist.
  • Diabetes patients - Metoprolol tartrate tablets may hide signs of low blood sugar, such as rapid heartbeat. Be sure to watch for other signs or low blood sugar. Low blood sugar may make you anxious, sweaty, weak, dizzy, drowsy, or faint. It may also make your vision change; give you a headache, chills, or tremors; or make you more hungry. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
  • Tell your doctor or dentist that you take metoprolol tartrate tablets before you receive any medical or dental care, emergency care, or surgery.
  • If you have a history of any severe allergic reaction, talk with your doctor. You may be at risk of an even more severe allergic reaction if you come into contact with the substance that caused your allergy. Some medicines used to treat severe allergies may also not work as well while you are using metoprolol tartrate tablets.
  • Lab tests, including liver function, kidney function, blood pressure, and complete blood cell counts, may be performed while you use metoprolol tartrate tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Metoprolol tartrate tablets should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using metoprolol tartrate tablets while you are pregnant. Metoprolol tartrate tablets is found in breast milk. If you are or will be breast-feeding while you use metoprolol tartrate tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of metoprolol tartrate tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; dry mouth or eyes; gas; headache; heartburn; light-headedness; nausea; stomach pain; stuffy or runny nose; tiredness; trouble sleeping; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue, unusual hoarseness); blue or unusually cold hands or feet; blurred vision or other vision changes; chest pain; chills, fever, or sore throat; fainting; hallucinations; mood or mental changes (eg, confusion, depression, short-term memory loss); pounding in the chest; ringing in the ears; severe dizziness or light-headedness; shortness of breath; slow or irregular heartbeat; swelling of the arms, hands, and feet; unusual bruising or bleeding; unusual tiredness or weakness; wheezing; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficult or slowed breathing; fainting; severe dizziness; very slow heart rate; weakness.

Proper storage of metoprolol tartrate tablets:

Store metoprolol tartrate tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep metoprolol tartrate tablets out of the reach of children and away from pets.

General information:

  • If you have any questions about metoprolol tartrate tablets, please talk with your doctor, pharmacist, or other health care provider.
  • Metoprolol tartrate tablets is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take metoprolol tartrate tablets or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about metoprolol tartrate tablets. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to metoprolol tartrate tablets. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using metoprolol tartrate tablets.

Issue Date: September 3, 2014
Database Edition 14.3.1.003
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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