Toprol-XL

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Treatment & Uses
Side Effects
Treating Overdose
Safety Information
Before Using

Generic Name: metoprolol (me TOE pro lol)
Brand Names: Lopressor, Metoprolol Succinate ER, Toprol-XL

What is Toprol-XL?

Feedback for Toprol-XL

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Toprol-XL is in a group of drugs called beta-blockers. Beta-blockers affect the heart and circulation (blood flow through arteries and veins).

Toprol-XL is used to treat angina (chest pain) and hypertension (high blood pressure). It is also used to treat or prevent heart attack.

Toprol-XL may also be used for other purposes not listed in this medication guide.

Important information know about Toprol-XL

You should not use Toprol-XL if you are allergic to metoprolol, or if you have a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate.

Before taking Toprol-XL, tell your doctor if you have pheochromocytoma, circulation problems, congestive heart failure, asthma or other breathing problems, diabetes, low blood pressure, depression, liver or kidney disease, a thyroid disorder, or myasthenia gravis.

Toprol-XL can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol, which could increase drowsiness and dizziness while you are taking Toprol-XL. Do not stop taking Toprol-XL without first talking to your doctor. Stopping suddenly may make your condition worse.

If you need to have any type of surgery, you may need to temporarily stop using Toprol-XL. Be sure the surgeon knows ahead of time that you are using this medicine.

Toprol-XL is only part of a complete program of treatment for hypertension that may also include diet, exercise, and weight control. Follow your diet, medication, and exercise routines very closely if you are being treated for hypertension.

Hypertension often has no symptoms, so you may not even feel that you have high blood pressure. Continue using this medicine as directed, even if you feel well. You may need to use blood pressure medication for the rest of your life.

Before taking Toprol-XL

You should not use Toprol-XL if you are allergic to metoprolol, or if you have a serious heart problem such as heart block, sick sinus syndrome, or slow heart rate.

If you have any of these other conditions, you may need a dose adjustment or special tests to safely use Toprol-XL:

pheochromocytoma;
problems with circulation (such as Raynaud's syndrome);
congestive heart failure;
asthma, bronchitis, emphysema;
diabetes;
low blood pressure;
depression;
liver or kidney disease;
a thyroid disorder; or
myasthenia gravis.

FDA pregnancy category C. It is not known whether Toprol-XL is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. Metoprolol can pass into breast milk and may harm a nursing baby. Do not use Toprol-XL without telling your doctor if you are breast-feeding a baby.

How should I take Toprol-XL?

Take Toprol-XL exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Take Toprol-XL with a full glass of water.

Take Toprol-XL at the same time every day.

Toprol-XL should be taken with food or just after a meal. A Toprol XL tablet can be divided in half if your doctor has told you to do so. The half tablet should be swallowed whole, without chewing or crushing. Chewing or crushing the pill could cause too much of the drug to be released at one time. Do not skip doses or stop taking Toprol-XL without first talking to your doctor. Stopping suddenly may make your condition worse.

To be sure Toprol-XL is helping your condition, your blood pressure will need to be checked on a regular basis. It is important that you not miss any scheduled visits to your doctor.

If you need to have any type of surgery, tell the surgeon that you are using Toprol-XL. You may need to briefly stop using Toprol-XL before having surgery.

Store Toprol-XL at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If your next dose is less than 4 hours away, skip the missed dose and take the medicine at the next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include slow or uneven heartbeats, shortness of breath, bluish-colored fingernails, dizziness, weakness or fainting.

What should I avoid while taking Toprol-XL?

Toprol-XL side effects

Get emergency medical help if you have any of these signs of an allergic reaction to Toprol-XL: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have any of these serious side effects:

slow or uneven heartbeats;
feeling light-headed, fainting;
feeling short of breath, even with mild exertion;
swelling of your ankles or feet;
nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
depression; or
cold feeling in your hands and feet.

Less serious Toprol-XL side effects may include:

vomiting;
decreased sex drive, impotence, or difficulty having an orgasm;
sleep problems (insomnia);
tired feeling; or
anxiety, nervousness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Toprol-XL?

Before taking Toprol-XL, tell your doctor if you are using:

digoxin (digitalis, Lanoxin);
clonidine (Catapres);
ritonavir (Norvir);
terbinafine (Lamisil);
anti-malaria medications such as chloroquine (Aralen) or hydroxychloroquine (Plaquenil, Quineprox);
medicine to treat depression or mental illness, such as bupropion (Wellbutrin, Zyban), fluoxetine (Prozac, Sarafem), paroxetine (Paxil), thioridazine (Mellaril), and others;
an MAO inhibitor such as isocarboxazid (Marplan), tranylcypromine (Parnate), phenelzine (Nardil), or selegiline (Eldepryl, Emsam);
a diabetes medication such as insulin, glyburide (Diabeta, Micronase, Glynase), glipizide (Glucotrol), chlorpropamide (Diabinese), or metformin (Glucophage);
a heart medication such as nifedipine (Procardia, Adalat), quinidine (Quinaglute, Quinidex), propafenone (Rythmol), reserpine (Serpasil), verapamil (Calan, Verelan, Isoptin), diltiazem (Cartia, Cardizem);
medicine for asthma or other breathing disorders, such as albuterol (Ventolin, Proventil), bitolterol (Tornalate), metaproterenol (Alupent), pirbuterol (Maxair), terbutaline (Brethaire, Brethine, Bricanyl), and theophylline (Theo-Dur, Theolair);
a diuretic (water pill) such as amiloride (Midamor, Moduretic), chlorthalidone (Hygroton, Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, HydroDiuril, Hyzaar, Lopressor, Vasoretic, Zestoretic), spironolactone (Aldactazide, Aldactone), triamterene (Dyrenium, Maxzide, Dyazide), torsemide (Demadex), and others; or
cold medicines, stimulant medicines, or diet pills.

This list is not complete and there may be other drugs that can interact with Toprol-XL. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

Where can I get more information?

Your pharmacist can provide more information about Toprol-XL.

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.