Geodon

Geodon is used for:

Treating acute agitation in patients with schizophrenia who require an injectable medicine. It may also be used for other conditions as determined by your doctor.

Geodon is an antipsychotic. It may work by altering the balance of certain chemicals that occur naturally in the brain, which are responsible for thinking and behavior.

Do NOT use Geodon if:

• you are allergic to any ingredient in Geodon
• you have recently had a heart attack, have severe heart failure, or have a history of certain types of irregular heartbeat (eg, long QT syndrome)
• you are taking astemizole, certain phenothiazines (eg, thioridazine), certain quinolone antibiotics (eg, moxifloxacin), cisapride, dofetilide, droperidol, halofantrine, levomethadyl, a macrolide immunosuppressive (eg, tacrolimus), mefloquine, methadone, pentamidine, pimozide, probucol, procainamide, quinidine, a serotonin receptor antagonist antiemetic (eg, dolesetron), sotalol, sparfloxacin, or terfenadine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Geodon :

Some medical conditions may interact with Geodon . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding
• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substances
• if you have considered or attempted suicide
• if you have heart disease, a slow heartbeat, low blood potassium or magnesium levels, low blood volume, a drug-induced movement disorder, diabetes, kidney or liver problems, a history of stroke, a history of low blood pressure, seizures, difficulty swallowing, Alzheimer disease, dementia, or breast cancer, or if you are overweight

Some MEDICINES MAY INTERACT with Geodon . Tell your health care provider if you are taking any other medicines, especially any of the following:

• Arsenic, astemizole, cisapride, class III antiarrhythmics (eg, amiodarone, sotalol), dofetilide, droperidol, halofantrine, IA and IC antiarrhythmics (eg, flecainide, procainamide, propafenone, quinidine), levomethadyl, macrolide immunosuppressives (eg, tacrolimus), macrolides and ketolides (eg, azithromycin, erythromycin), mefloquine, methadone, pentamidine, phenothiazines (eg, thioridazine), pimozide, probucol, quinolones (eg, ciprofloxacin, moxifloxacin), serotonin receptor antagonist antiemetics (eg, dolesetron), sparfloxacin, streptogramins (eg, mitomycin, pristinamycin), or terfenadine because the risk of side effects such as abnormal heart rhythms may be increased
• Carbamazepine because it may decrease Geodon 's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Geodon may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Geodon :

Use Geodon as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Geodon is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Geodon at home, a health care provider will teach you how to use it. Be sure you understand how to use Geodon . Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.
• Do not use Geodon if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged.
• Keep this product, as well as syringes and needles, out of the reach of children and pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal.
• If you miss a dose of Geodon , use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Geodon .

Important safety information:

• Geodon may cause drowsiness, dizziness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Geodon with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Geodon ; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
• Geodon may cause dizziness, lightheadedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
• Do not become overheated in hot weather or while you are being active; heatstroke may occur.
• Geodon is intended for short-term control of acute agitation symptoms. If you require continuous treatment for your condition, your doctor may switch you to an oral medicine.
• Geodon may increase your risk for developing diabetes or increase blood sugar levels. High blood sugar levels can cause serious problems if left untreated.
• Diabetes patients - Geodon may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
• Serotonin syndrome is a possibly fatal syndrome that can be caused by Geodon . Your risk may be greater if you take Geodon with certain other medicines (eg, "triptans," monoamine oxidase inhibitors [MAOIs]). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.
• Lab tests, including electrolyte levels or fasting blood sugar levels, may be performed while you use Geodon . These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
• Use Geodon with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness and lightheadedness upon sitting or standing up.
• Geodon should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.
• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Geodon while you are pregnant. It is not known if Geodon is found in breast milk. Do not breast-feed while taking Geodon ..

Possible side effects of Geodon :

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth; feeling unusually tired or sleepy; headache; increased cough or runny nose; loss of appetite; nausea; pain at the injection site; upset stomach.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); altered mental abilities, including lack of response to your surroundings; change in amount of urine; change in vision; difficulty swallowing; fainting or loss of consciousness; fast or irregular heartbeat; fever; high blood sugar (increased thirst, increased urination, confusion, flushing, rapid breathing, or fruity breath odor); inability to move; increased body heat; muscle rigidity; muscle spasms or twitching; pounding in the chest; prolonged or painful erection; seizures; sweating; uncontrolled movements (especially of face or tongue); unusual mood or mental changes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org), or emergency room immediately. Symptoms may include fainting; irregular heartbeat; seizure; slurring of speech; uncontrolled movement of the head and neck.

Geodon is usually handled and stored by a health care provider. If you are using Geodon at home, store Geodon as directed by your pharmacist or health care provider. Keep Geodon , as well as needles and syringes, out of the reach of children and away from pets.

General information:

• If you have any questions about Geodon , please talk with your doctor, pharmacist, or other health care provider.
• Geodon is to be used only by the patient for whom it is prescribed. Do not share it with other people.
• If your symptoms do not improve or if they become worse, check with your doctor.

This information is a summary only. It does not contain all information about Geodon . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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