Ziprasidone Pregnancy and Breastfeeding Warnings
Ziprasidone is also known as: Geodon
Ziprasidone Pregnancy Warnings
Ziprasidone has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of developmental toxicity including possible teratogenic effects, an increased incidence of fetal structural abnormalities, an increase in the number of offspring born dead, and a decrease in postnatal survival. Studies in female animals reported that ziprasidone increased time to copulation and reduced the rate of fertility. There are no controlled data in human pregnancy. Neonates exposed to antipsychotic drugs during the third trimester of pregnancy are at risk for extrapyramidal and/or withdrawal symptoms following delivery. There have been reports of agitation, hypertonia, hypotonia, tremor, somnolence, respiratory distress and feeding disorder in these neonates. These complications have varied in severity; while in some cases symptoms have been self-limited, in other cases neonates have required intensive care unit support and prolonged hospitalization. Ziprasidone is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.
Ziprasidone Breastfeeding Warnings
There are no data on the excretion of ziprasidone into human milk. The manufacturer recommends that due to the potential for serious adverse reactions in nursing infants, women receiving ziprasidone should not breast-feed.
See Also...
- Ziprasidone use while Breastfeeding (in more detail)
- ziprasidone Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
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