Generic Name: risperidone (oral) (ris PER i done)
Brand names: Risperdal, Risperdal M-Tab, Risperdal Consta
What is risperidone?
Risperidone is an antipsychotic medication. It works by changing the effects of chemicals in the brain.
Risperidone is used to treat schizophrenia and symptoms of bipolar disorder (manic depression). It is also used in autistic children to treat symptoms of irritability.
Risperidone may also be used for purposes other than those listed in this medication guide.
Important information about risperidone
Risperidone is not for use in psychotic conditions related to dementia. This medication may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.
Do not give Risperidone to a child without a doctor's advice.
While you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking this medication.
Risperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of risperidone.
Stop using risperidone and call your doctor at once if you have fever, stiff muscles, confusion, sweating, fast or uneven heartbeats, restless muscle movements in your face or neck, tremor (uncontrolled shaking), trouble swallowing, feeling light-headed, or fainting.
Before taking risperidone
Risperidone is not for use in psychotic conditions related to dementia. Risperidone may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not use this medication if you are allergic to risperidone.
You should not use this medication if you are allergic to risperidone.
To make sure you can safely take risperidone, tell your doctor if you have any of these other conditions:
heart disease, high blood pressure, heart rhythm problems;
high cholesterol or triglycerides (a type of fat in the blood);
a history of heart attack or stroke;
a history of low white blood cell (WBC) counts;
a history of breast cancer;
seizures or epilepsy;
diabetes (risperidone may raise your blood sugar);
a history of suicidal thoughts;
Parkinson's disease; or
Risperidone may cause you to have high blood sugar (hyperglycemia). Talk to your doctor if you have any signs of hyperglycemia such as increased thirst or urination, excessive hunger, or weakness. If you are diabetic, check your blood sugar levels on a regular basis while you are taking risperidone.
The risperidone orally disintegrating tablet may contain phenylalanine. Talk to your doctor before using this form of risperidone if you have phenylketonuria (PKU).
FDA pregnancy category C. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking risperidone, do not stop taking it without your doctor's advice. Risperidone can pass into breast milk and may harm a nursing baby. You should not breast-feed while taking risperidone. Do not use this medication without telling your doctor if you are breast-feeding a baby.
See also: Risperidone pregnancy and breastfeeding warnings (in more detail)
Do not give this medication to a child without a doctor's advice.
How should I take risperidone?
Take risperidone exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.
Risperidone can be taken with or without food.
To take risperidone orally disintegrating tablets (Risperdal M-Tabs):
Keep the tablet in its blister pack until you are ready to take the medicine. Open the package and peel back the foil from the tablet blister. Do not push a tablet through the foil or you may damage the tablet.
Using dry hands, remove the tablet and place it in your mouth. It will begin to dissolve right away.
Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing.
Swallow several times as the tablet dissolves. If desired, you may drink liquid after the tablet is completely dissolved.
It is important to take risperidone regularly to get the most benefit. Get your prescription refilled before you run out of medicine completely.
Measure the liquid form of risperidone with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.
Do not mix the liquid form of risperidone with cola or tea.
It may take several weeks of using this medicine before your symptoms improve. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve.
Store risperidone at room temperature away from moisture, light, and heat. Do not allow the liquid form of risperidone to freeze.
See also: Risperidone dosage (in more detail)
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
Overdose symptoms may include drowsiness, fast heart rate, feeling light-headed, fainting, and restless muscle movements in your eyes, tongue, jaw, or neck.
What should I avoid while taking risperidone?
While you are taking risperidone, you may be more sensitive to temperature extremes such as very hot or cold conditions. Avoid getting too cold, or becoming overheated or dehydrated. Drink plenty of fluids, especially in hot weather and during exercise. It is easier to become dangerously overheated and dehydrated while you are taking risperidone.
Risperidone may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Drinking alcohol can increase certain side effects of risperidone.
See also: Risperidone and alcohol (in more detail)
Risperidone side effects
Get emergency medical help if you have any of these signs of an allergic reaction to risperidone: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking risperidone and call your doctor at once if you have a serious side effect such as:
fever, stiff muscles, confusion, sweating, fast or uneven heartbeats;
restless muscle movements in your eyes, tongue, jaw, or neck;
drooling, tremor (uncontrolled shaking);
fever, chills, body aches, flu symptoms;
white patches or sores inside your mouth or on your lips;
feeling like you might pass out; or
penis erection that is painful or lasts 4 hours or longer.
Less serious risperidone side effects may include:
feeling hot or cold;
drowsiness, tired feeling;
dry mouth, increased appetite;
feeling restless or anxious;
sleep problems (insomnia);
nausea, vomiting, stomach pain, constipation;
cough, sore throat, runny or stuffy nose; or
mild skin rash.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Risperidone side effects (in more detail)
What other drugs will affect risperidone?
Before you take risperidone, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by risperidone.
Also tell your doctor if you are taking any of the following medicines:
carbamazepine (Carbatrol, Equetro, Tegretol);
cimetidine (Tagamet) or ranitidine (Zantac);
fluoxetine (Prozac, Sarafem, Symbyax) or paroxetine (Paxil);
phenytoin (Dilantin) or valproic acid (valproate, Depakene, Stavzor);
rifampin (Rifadin, Rimactane, Rifater); or
medicines used to treat Parkinson's Disease such as levodopa (Dopar, Larodopa, Sinemet, Atamet, others), bromocriptine (Parlodel, others), pergolide (Permax), pramipexole (Mirapex), or ropinirole (Requip).
This list is not complete and there may be other drugs that can interact with risperidone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.
More Risperidone resources
- risperidone MedFacts Consumer Leaflet (Wolters Kluwer)
- risperidone Advanced Consumer (Micromedex) - Includes Dosage Information
- Risperdal Prescribing Information (FDA)
- Risperdal MedFacts Consumer Leaflet (Wolters Kluwer)
- Risperdal Consta Prescribing Information (FDA)
- Risperdal Consta Advanced Consumer (Micromedex) - Includes Dosage Information
- Risperdal M-Tab orally disintegrating tablets MedFacts Consumer Leaflet (Wolters Kluwer)
- Risperidone Prescribing Information (FDA)
- Risperidone Monograph (AHFS DI)
- Risperidone Professional Patient Advice (Wolters Kluwer)
Compare Risperidone with other medications
Where can I get more information?
- Your pharmacist can provide more information about risperidone.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Copyright 1996-2011 Cerner Multum, Inc. Version: 20.01. Revision Date: 11/2/2011 1:07:15 PM.