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Cardene SR sustained-release capsules

Generic Name: nicardipine (nye-KAR-di-peen)
Brand Name: Cardene SR

Cardene SR sustained-release capsules is used for:

Treating high blood pressure. It may be used alone or in combination with other high blood pressure medicines. It may also be used for other conditions as determined by your doctor.

Cardene SR sustained-release capsules is a calcium channel blocker. It works by relaxing the blood vessels, which helps to lower blood pressure.

Do NOT use Cardene SR sustained-release capsules if:

  • you are allergic to any ingredient in Cardene SR sustained-release capsules
  • you are breast-feeding
  • you have advanced narrowing of your aorta (stenosis)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Cardene SR sustained-release capsules:

Some medical conditions may interact with Cardene SR sustained-release capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant or planning to become pregnant
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have angina (chest pain), congestive heart failure (CHF) or other heart problems, adrenal glad problems (eg, pheochromocytoma), liver or kidney problems, low blood pressure, or lung congestion associated with heart attack, or have had a stroke
  • you have CHF and you are taking a beta-blocker, or you are having beta-blocker withdrawal

Some MEDICINES MAY INTERACT with Cardene SR sustained-release capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Cimetidine because it may increase the risk of Cardene SR sustained-release capsules's side effects
  • Cyclosporine or digoxin because the risk of their side effects may be increased by Cardene SR sustained-release capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Cardene SR sustained-release capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Cardene SR sustained-release capsules:

Use Cardene SR sustained-release capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take Cardene SR sustained-release capsules by mouth with or without food, but do not take with a high-fat meal.
  • Swallow Cardene SR sustained-release capsules whole. Do not break, crush, or chew before swallowing.
  • Do not eat grapefruit or drink grapefruit juice while taking Cardene SR sustained-release capsules unless your doctor directs you otherwise.
  • If you miss a dose of Cardene SR sustained-release capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Cardene SR sustained-release capsules.

Important safety information:

  • Cardene SR sustained-release capsules may cause dizziness or fainting. These effects may be worse if you take it with alcohol or certain medicines. Use Cardene SR sustained-release capsules with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Patients being treated for high blood pressure often feel tired or run down for a few weeks after beginning therapy. Continue taking your medicine even though you may not feel quite "normal." Contact your doctor or pharmacist about any new symptoms.
  • Maximum lowering of blood pressure occurs approximately 1 to 2 hours after taking the medicine. Blood pressure should be taken 1 to 2 hours after the medicine has been taken.
  • Tell your doctor or dentist that you take Cardene SR sustained-release capsules before you receive any medical or dental care, emergency care, or surgery.
  • Additional monitoring of your dose or condition may be necessary if you are using intravenous (IV) calcium.
  • Lab tests, including blood pressure, electrocardiogram (ECG) readings, and monitoring of heart rate, may be performed while you use Cardene SR sustained-release capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Cardene SR sustained-release capsules while you are pregnant. Cardene SR sustained-release capsules is found in breast milk. Do not breast-feed while taking Cardene SR sustained-release capsules.

If you suddenly stop taking Cardene SR sustained-release capsules, you may experience WITHDRAWAL symptoms including increased chest pain (angina) and more frequent chest pain.

Possible side effects of Cardene SR sustained-release capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); calf pain, swelling, or redness; confusion; fainting; fast or irregular heartbeat; fever; increased chest pain; pounding in the chest; shortness of breath or wheezing; swelling of the feet, ankles, or hands; unusual bruising or bleeding.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include confusion; drowsiness; fast or slowed heart rate; flushing; slurred speech; weakness.

Proper storage of Cardene SR sustained-release capsules:

Store Cardene SR sustained-release capsules between 59 and 86 degrees F (15 and 30 degrees C) in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Cardene SR sustained-release capsules out of the reach of children and away from pets.

General information:

  • If you have any questions about Cardene SR sustained-release capsules, please talk with your doctor, pharmacist, or other health care provider.
  • Cardene SR sustained-release capsules is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take Cardene SR sustained-release capsules or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Cardene SR sustained-release capsules. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Cardene SR sustained-release capsules. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Cardene SR sustained-release capsules.

Issue Date: April 2, 2014
Database Edition 14.2.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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