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Auranofin

Generic Name: auranofin (or-RAIN-oh-fin)
Brand Name: Ridaura

Auranofin contains gold, which can build up in the blood and become toxic. Report any symptom suggesting toxicity (rash, mouth sores, persistent diarrhea, indigestion, metallic taste, unusual bleeding or bruising, itching, blood in the urine, fainting) to your health care provider immediately.


Auranofin is used for:

Managing rheumatoid arthritis in patients who do not respond to or are intolerant of other medicines.

Auranofin is an antirheumatic agent. The way auranofin works is not fully understood.

Do NOT use auranofin if:

  • you are allergic to any ingredient in auranofin
  • you have a history of blood and bone marrow disorders or disease
  • you have inflammation and peeling of the skin, scar tissue on the lungs, or serious bowel inflammation
  • you are taking penicillamine

Contact your doctor or health care provider right away if any of these apply to you.

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Before using auranofin:

Some medical conditions may interact with auranofin. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have small red spots under the skin, unusual bleeding or bruising, eczema, liver disease, kidney problems, lupus, yellowing of the skin or eyes, inflammation of the skin or mouth, blood circulation problems, chronic arthritis accompanied by dry mouth/eyes, itching, skin rash, or colitis
  • if you are receiving radiation therapy or are debilitated

Some MEDICINES MAY INTERACT with auranofin. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Penicillamine because the risk of serious blood or kidney problems may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if auranofin may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use auranofin:

Use auranofin as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Auranofin may be taken with or without food.
  • Auranofin comes with an additional patient leaflet. Read it carefully and reread it each time you get auranofin refilled.
  • If you miss a dose of auranofin, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use auranofin.

Important safety information:

  • Three to six months may pass before you feel the full effect of auranofin. Do not stop taking auranofin without checking with your doctor.
  • Auranofin may cause increased sensitivity to the sun. Avoid exposure to the sun, sunlamps, or tanning booths until you know how you react to auranofin. Use a sunscreen or wear protective clothing if you must be outside for a prolonged period.
  • LAB TESTS, including complete blood cell counts, may be performed to monitor your progress. Be sure to keep all doctor and lab appointments.
  • Auranofin is not recommended for use in CHILDREN. Safety and effectiveness have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using auranofin during pregnancy. It is unknown if auranofin is excreted in breast milk. Do not breast-feed while taking auranofin.

Possible side effects of auranofin:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abdominal pain; constipation; diarrhea; gas; inflammation of the eye, mouth, or skin; itching; loose stools; nausea; stomach pain; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding disorder; blood in the urine; fainting; indigestion; itching; metallic taste; mouth sores; peeling skin; persistent diarrhea; purple blotches or other unusual skin spots; rash; shortness of breath; sore throat; unusual bleeding or bruising; unusual weakness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include diarrhea; fever; nausea; skin disorders (hives and severe itching); vomiting.

Proper storage of auranofin:

Store auranofin at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep auranofin out of the reach of children and away from pets.

General information:

  • If you have any questions about auranofin, please talk with your doctor, pharmacist, or other health care provider.
  • Auranofin is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take auranofin or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about auranofin. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to auranofin. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using auranofin.

Issue Date: July 2, 2014
Database Edition 14.3.1.001
Copyright © 2014 Wolters Kluwer Health, Inc.

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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