A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.
All nonsteroidal anti-inflammatory agents (NSAIDs) differ in structure but they all have similar antipyretic, anti-inflammatory and analgesic properties.
NSAIDs work by blocking the cyclo-oxygenase (COX) enzyme, so inhibit production of prostaglandins and thromboxanes, which are produced as part of the inflammatory response.
There are two types of COX enzymes, COX-1 and COX-2. COX-1 is expressed in most tissues, including platelets. COX-2 is induced in inflammatory cells when they are activated and the primary inflammatory cytokines (interleukin-1 and tumor necrosis factor alpha). COX-2 enzyme is responsible for production of mediators of inflammation. Most NSAIDs are inhibitors of both isoenzymes. The anti-inflammatory action of NSAIDs is mainly due to inhibition of COX-2, and their unwanted side effects are largely due to inhibition of COX-1.
There can be considerable variation in individual patient response and tolerance to different NSAIDs.
Drug Name  ( View by: Brand | Generic )
|
Reviews |
Avg. Ratings |
Cambia (Pro, More...)
generic name: diclofenac
|
2 Review(s) |
Rate It! | 10 |
Motrin Infant Drops (More...)
generic name: ibuprofen
|
1 Review(s) |
Rate It! | 10 |
Children's Motrin (More...)
generic name: ibuprofen
|
2 Review(s) |
Rate It! | 9.7 |
Advil Liqui-Gels (Pro, More...)
generic name: ibuprofen
|
5 Review(s) |
Rate It! | 9.5 |
Orudis (Pro, More...)
generic name: ketoprofen
|
1 Review(s) |
Rate It! | 9.5 |
Clinoril (Pro, More...)
generic name: sulindac
|
2 Review(s) |
Rate It! | 9.0 |
Midol Extended Relief (More...)
generic name: naproxen
|
1 Review(s) |
Rate It! | 9.0 |
Motrin Migraine Pain (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 9.0 |
Orudis KT (More...)
generic name: ketoprofen
|
3 Review(s) |
Rate It! | 9.0 |
Arthrotec (Pro, More...)
generic name: diclofenac/misoprostol
|
19 Review(s) |
Rate It! | 8.7 |
Lodine XL (More...)
generic name: etodolac
|
0 Review(s) |
Rate It! | 8.5 |
Nalfon (Pro, More...)
generic name: fenoprofen
|
1 Review(s) |
Rate It! | 8.5 |
Motrin IB (Pro, More...)
generic name: ibuprofen
|
2 Review(s) |
Rate It! | 8.4 |
Ansaid (Pro, More...)
generic name: flurbiprofen
|
2 Review(s) |
Rate It! | 8.3 |
Cataflam (Pro, More...)
generic name: diclofenac
|
15 Review(s) |
Rate It! | 8.3 |
Feldene (Pro, More...)
generic name: piroxicam
|
10 Review(s) |
Rate It! | 8.1 |
Vimovo (Pro, More...)
generic name: esomeprazole/naproxen
|
6 Review(s) |
Rate It! | 8.1 |
Nuprin (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 8.0 |
Oruvail (Pro, More...)
generic name: ketoprofen
|
0 Review(s) |
Rate It! | 8.0 |
Voltaren (Pro, More...)
generic name: diclofenac
|
60 Review(s) |
Rate It! | 8.0 |
Voltaren-XR (Pro, More...)
generic name: diclofenac
|
4 Review(s) |
Rate It! | 7.8 |
Indocin SR (Pro, More...)
generic name: indomethacin
|
4 Review(s) |
Rate It! | 7.7 |
Lodine (Pro, More...)
generic name: etodolac
|
6 Review(s) |
Rate It! | 7.6 |
Naprelan (Pro, More...)
generic name: naproxen
|
9 Review(s) |
Rate It! | 7.6 |
Toradol (Pro, More...)
generic name: ketorolac
|
52 Review(s) |
Rate It! | 7.6 |
Naprosyn (Pro, More...)
generic name: naproxen
|
10 Review(s) |
Rate It! | 7.5 |
Toradol IM (More...)
generic name: ketorolac
|
3 Review(s) |
Rate It! | 7.5 |
Aleve (More...)
generic name: naproxen
|
32 Review(s) |
Rate It! | 7.2 |
Indocin (Pro, More...)
generic name: indomethacin
|
13 Review(s) |
Rate It! | 7.2 |
Advil (Pro, More...)
generic name: ibuprofen
|
11 Review(s) |
Rate It! | 7.1 |
EC-Naprosyn (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 7.0 |
Motrin (Pro, More...)
generic name: ibuprofen
|
8 Review(s) |
Rate It! | 7.0 |
Sprix (Pro, More...)
generic name: ketorolac
|
7 Review(s) |
Rate It! | 7.0 |
Anaprox (More...)
generic name: naproxen
|
3 Review(s) |
Rate It! | 6.9 |
Mobic (Pro, More...)
generic name: meloxicam
|
75 Review(s) |
Rate It! | 6.9 |
Ponstel (Pro, More...)
generic name: mefenamic acid
|
11 Review(s) |
Rate It! | 6.9 |
Relafen (Pro, More...)
generic name: nabumetone
|
22 Review(s) |
Rate It! | 6.9 |
Daypro (Pro, More...)
generic name: oxaprozin
|
3 Review(s) |
Rate It! | 6.2 |
Zipsor (Pro, More...)
generic name: diclofenac
|
17 Review(s) |
Rate It! | 6.1 |
IBU (Pro, More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 6.0 |
IBU-200 (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 5.5 |
All Day Pain Relief (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 5.0 |
Midol Maximum Strength Cramp Formula (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 5.0 |
Toradol IV/ IM (More...)
generic name: ketorolac
|
1 Review(s) |
Rate It! | 4.5 |
Duexis (Pro, More...)
generic name: famotidine/ibuprofen
|
0 Review(s) |
Rate It! | 4.0 |
Indocin IV (More...)
generic name: indomethacin
|
1 Review(s) |
Rate It! | 2.0 |
Advil Migraine (Pro, More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 1.0 |
A-G Profen (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Actiprofen (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Actron (More...)
generic name: ketoprofen
|
0 Review(s) |
Rate It! | 0.0 |
Addaprin (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Advil Children's (Pro, More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Advil Infant's Concentrated Drops (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Advil Junior Strength (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Aflaxen (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 0.0 |
All Day Relief (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Anaprox-DS (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Caldolor (Pro, More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Childrens Ibuprofen Berry (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Comfort Pac with Naproxen (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Genpril (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Haltran (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Leader Naproxen Sodium (More...)
generic name: naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Meclomen (More...)
generic name: meclofenamate
|
0 Review(s) |
Rate It! | 0.0 |
Midol IB (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Motrin Childrens (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Motrin Junior Strength (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
NeoProfen (Pro, More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Prevacid NapraPAC (Pro, More...)
generic name: lansoprazole/naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Prevacid NapraPAC 375 (More...)
generic name: lansoprazole/naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Prevacid NapraPAC 500 (More...)
generic name: lansoprazole/naproxen
|
0 Review(s) |
Rate It! | 0.0 |
Q-Profen (More...)
generic name: ibuprofen
|
0 Review(s) |
Rate It! | 0.0 |
Tolectin (Pro, More...)
generic name: tolmetin
|
0 Review(s) |
Rate It! | 0.0 |
Tolectin 600 (More...)
generic name: tolmetin
|
0 Review(s) |
Rate It! | 0.0 |
Tolectin DS (More...)
generic name: tolmetin
|
0 Review(s) |
Rate It! | 0.0 |
