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Tepezza: Uses, How It Works, and Common Side Effects

Tepezza is used to treat thyroid eye disease to reduce the symptoms of eye bulging, double vision, eye pain, redness, and swelling.

Video transcript

Tepezza is used to treat thyroid eye disease to reduce the symptoms of eye bulging, double vision, eye pain, redness, and swelling.

This medication is an insulin-like growth factor-1 receptor inhibitor. By blocking a protein called IGF-1R, it reduces the release of chemicals that contribute to inflammation in the eye.

Tepezza is given as an intravenous infusion every 3 weeks for a total of 8 doses. Each infusion takes 60 to 90 minutes to complete.

Common Tepezza side effects include muscle spasms, nausea, diarrhea, headache, tiredness, high blood sugar, hair loss, hearing problems, dry skin, altered sense of taste, weight loss, and nail problems.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Always consult with your healthcare provider.

Referenes:
1. Drugs.com. Updated Sept 2025. Tepezza: Package Insert / Prescribing Info. Retrieved from https://www.drugs.com/pro/tepezza.html
2. Tepezza [package insert]. Updated Aug 2025. Horizon Therapeutics USA, Inc. Retrieved from: https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=3e6c54a1-cefd-4a5b-a855-ab9f268b6cce
Prepared and presented by a registered pharmacist from Drugs.com, this content delivers clinically reviewed, evidence-based information for educational use. Always seek the guidance of a healthcare professional for personal medical decisions.

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