Yorvipath Side Effects

Generic name: palopegteriparatide

Medically reviewed by Drugs.com. Last updated on Oct 10, 2024.

Note: This document provides detailed information about Yorvipath.

Applies to palopegteriparatide: parenteral prefilled injection pen Side Effects associated with palopegteriparatide. Some dosage forms listed on this page may not apply specifically to the brand name Yorvipath.

Applies to palopegteriparatide: parenteral prefilled injection pen.

Side effects include:

Most common adverse reactions (≥5%): injection site reactions, vasodilatory signs and symptoms, headache, diarrhea, back pain, hypercalcemia, oropharyngeal pain.

For healthcare professionals

Applies to palopegteriparatide: subcutaneous solution.

General adverse events

Adverse reactions occurring in at least 5% of patients included elevated albumin-corrected serum calcium, injection site reactions, vasodilatory signs and symptoms, headache, diarrhea, back pain, hypercalcemia, and oropharyngeal pain.^[Ref]

Cardiovascular

• Very common (10% or more): Vasodilatory signs and symptoms (28%)

Gastrointestinal

• Very common (10% or more): Diarrhea (10%)

Hypersensitivity

• Frequency not reported: Hypersensitivity reactions such as anaphylaxis, angioedema, and urticaria have been observed with parathyroid hormone analogs

Immunologic

• Common (1% to 10%): Anti-drug antibodies

Local

• Very common (10% or more): Injection-site reactions such as bruising, erythema, and rash (39%)

Metabolic

• Very common (10% or more): Elevated albumin-corrected serum calcium greater than 10.6 mg/dL (54.1%), elevated albumin-corrected serum calcium greater than 12 mg/dL (13.1%)
• Common (1% to 10%): Hypercalcemia, symptomatic hypercalcemia

Musculoskeletal

• Common (1% to 10%): Back/flank/spinal pain

Nervous system

• Very common (10% or more): Headache (21%)

Oncologic

• Postmarketing reports: Osteosarcoma (with use of teriparatide)

Respiratory

• Common (1% to 10%): Oropharyngeal pain

See also:

Further information

Yorvipath side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer