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Uridine Side Effects

For the Consumer

Applies to uridine: oral granule

As well as its needed effects, uridine may cause unwanted side effects that require medical attention.

Major Side Effects

If any of the following side effects occur while taking uridine, check with your doctor immediately:

Incidence not known:
  • Rash or itching skin

Minor Side Effects

Some uridine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common:
  • Vomiting
Less common:
  • Diarrhea
  • Nausea

For Healthcare Professionals

Applies to uridine: oral granule

Gastrointestinal

Very common (10% or more): Vomiting (10%)
Common (1% to 10%): Nausea, diarrhea[Ref]

General

-In 135 patients who had either received an overdose of fluorouracil or capecitabine or presented with severe or life-threatening toxicities within 96 hours, uridine triacetate was discontinued for adverse reactions in 2 patients; serious adverse reactions (Grade 3 nausea and vomiting) were seen in 1 patient.
-In 4 patients with hereditary orotic aciduria ranging in age from 3 to 19 years (3 males, 1 female) who received this drug for at least 9 months at dosages up to 120 mg/kg once a day, no adverse reactions were reported.[Ref]

References

1. "Product Information. Xuriden (uridine)." Wellstat Therapeutics Corp, Gaithersburg, MD.

2. "Product Information. Vistogard (uridine)." BTG International Inc, West Conshohocken, PA.

It is possible that some side effects of uridine may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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