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SRC Expectorant Side Effects

Generic name: guaifenesin / hydrocodone / pseudoephedrine

Medically reviewed by Drugs.com. Last updated on Feb 2, 2024.

Note: This document provides detailed information about SRC Expectorant Side Effects associated with guaifenesin / hydrocodone / pseudoephedrine. Some dosage forms listed on this page may not apply specifically to the brand name SRC Expectorant.

Applies to guaifenesin / hydrocodone / pseudoephedrine: oral liquid.

Important warnings This medicine can cause some serious health issues

MISUSE OF OPIOID MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH. Keep the medication in a place where others cannot get to it.

Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

This medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Stop using this medicine and call your doctor at once if you have:

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For healthcare professionals

Applies to guaifenesin/hydrocodone/pseudoephedrine: oral liquid, oral tablet.

General

The most common adverse events were sedation (somnolence, mental clouding, lethargy), impaired mental and physical performance, lightheadedness, dizziness, headache, dry mouth, nausea, vomiting, constipation, tachycardia, arrhythmias including premature ventricular contractions, CNS stimulation including anxiety, restlessness, nervousness, tremor, and irritability.[Ref]

Respiratory

Cardiovascular

Psychiatric

Nervous system

Serotonin syndrome has been reported with concomitant opioids and serotonergic drugs.

Gastrointestinal

Dermatologic

Genitourinary

Endocrine

Adrenal insufficiency has been reported with opioid use, most often following greater than one month of use. Androgen deficiency has been reported with chronic opioid use.

Musculoskeletal

Ocular

Metabolic

References

1. (2017) "Product Information. Hycofenix (guaifenesin / hydrocodone / pseudoephedrine)." Mission Pharmacal Company

More about SRC Expectorant (guaifenesin / hydrocodone / pseudoephedrine)

Patient resources

Other brands

Entex HC, Hycofenix, Su-Tuss HD Elixir

Related treatment guides

Further information

SRC Expectorant side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.