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Spy Agent Green Side Effects

Generic name: indocyanine green

Medically reviewed by Last updated on Dec 9, 2021.

Note: This document contains side effect information about indocyanine green. Some of the dosage forms listed on this page may not apply to the brand name Spy Agent Green.

For the Consumer

Applies to indocyanine green: intravenous powder for solution

Side effects requiring immediate medical attention

Along with its needed effects, indocyanine green (the active ingredient contained in Spy Agent Green) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking indocyanine green:

Incidence not known

  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • hives or welts, itching, skin rash
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness of the skin
  • tightness in the chest
  • unusual tiredness or weakness

For Healthcare Professionals

Applies to indocyanine green: injectable powder for injection


Frequency not reported: Anaphylactic or urticarial reactions[Ref]

More about Spy Agent Green (indocyanine green)

Professional resources

Related treatment guides


1. "Product Information. IC-Green (indocyanine green)." Akorn Inc (2007):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.