Shingrix Side Effects
Generic Name: zoster vaccine, inactivated
Medically reviewed by Drugs.com. Last updated on Nov 7, 2020.
Note: This document contains side effect information about zoster vaccine, inactivated. Some of the dosage forms listed on this page may not apply to the brand name Shingrix.
For the Consumer
Applies to zoster vaccine, inactivated: intramuscular suspension
Side effects requiring immediate medical attention
Along with its needed effects, zoster vaccine, inactivated (the active ingredient contained in Shingrix) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking zoster vaccine, inactivated:
- Ankle, knee, or great toe joint pain
- blurred vision
- decreased vision
- eye pain
- fever greater than 39 degree Celsius
- joint stiffness or swelling
- lower back or side pain
- swollen, painful, or tender lymph glands in the neck, armpit, or groin
Side effects not requiring immediate medical attention
Some side effects of zoster vaccine, inactivated may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- difficulty in moving
- muscle aches, cramps, pains, or stiffness
- pain, redness, and swelling at the injection site
- stomach pain
- unusual tiredness or weakness
- general feeling of discomfort or illness
- itching at the injection site
For Healthcare Professionals
Applies to zoster vaccine, inactivated: intramuscular powder for injection
Very common (10% or more): Local pain (88.4%), local redness (38.7%)
Very common (10% or more): Fatigue (57%), shivering (35.8%), fever (27.8%)
Common (1% to 10%): Malaise
Uncommon (0.1% to 1%): Death[Ref]
Deaths were reported for 0.8% of patients in the treatment group during the first year after vaccination versus 0.9% of placebo patients. Causes of death were consistent with those generally reported in adult and elderly populations.[Ref]
Very common (10% or more): Headache (50.6%)
Common (1% to 10%): Dizziness[Ref]
Very common (10% or more): Gastrointestinal symptoms (24.3%)
Common (1% to 10%): Nausea[Ref]
Rare (less than 0.1%): Optic ischemic neuropathy[Ref]
Very rare (less than 0.01%): Lymphadenitis[Ref]
Very common (10% or more): Myalgia (56.9%)
Common (1% to 10%): Chills, arthralgia[Ref]
1. "Product Information. Shingrix (zoster vaccine, inactivated)." GlaxoSmithKline, Research Triangle Park, NC.
Frequently asked questions
More about Shingrix (zoster vaccine, inactivated)
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- 502 Reviews
- Drug class: viral vaccines
- Latest FDA Alerts (1)
- FDA Approval History
Related treatment guides
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.