Senokot S Side Effects
Generic name: docusate/senna
Note: This document provides detailed information about Senokot S Side Effects associated with docusate/senna. Some dosage forms listed on this page may not apply specifically to the brand name Senokot S.
Applies to docusate/senna: oral capsule, oral tablet.
Important warnings
This medicine can cause some serious health issues
Use exactly as directed on the label, or as prescribed by your doctor.
Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Stop using docusate and senna and call your doctor at once if you have:
Common side effects may include:
-
gas, bloating;
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diarrhea; or
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mild nausea.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.
For healthcare professionals
Applies to docusate/senna: oral capsule, oral tablet.
Gastrointestinal adverse events
Gastrointestinal side effects of docusate have included gastrointestinal cramping.
Gastrointestinal side effects of senna have included esophageal impaction and duodenal bezoars. These effects have been reported in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (commercially available as Perdiem Overnight Relief).[Ref]
Hypersensitivity
Hypersensitivity side effects of senna have rarely included occupational sensitization to senna.[Ref]
One case has been reported involving a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]
Metabolic
Metabolic side effects of docusate have included at least one case report of hypomagnesemia.[Ref]
Metabolic abnormalities reported include hypomagnesemia in one woman who took docusate chronically throughout her pregnancy. Magnesium levels returned to normal following discontinuation of docusate.[Ref]
Musculoskeletal
Musculoskeletal side effects of senna have rarely included finger clubbing.[Ref]
Dermatologic
Dermatologic side effects of docusate have included rash.[Ref]
References
1. (2001) "Product Information. Colace (docusate)." Roberts Pharmaceutical Corporation
2. Dorr MB, Johnson RD, Jensen B, Magner D, Marbury T, Talbo GH (1999) "Pharmacokinetics of sparfloxacin in patients with renal impairment." Clin Ther, 21, p. 1202-15
3. Helin T, Makinen-Kiljunen S (1996) "Occupational asthma and rhinoconjunctivitis caused by senna." Allergy, 51, p. 181-4
4. Malmquist J, Ericsson B, Hulten-Nosslin MB, Jeppsson JO, Ljungberg O (1980) "Finger clubbing and aspartylglucosamine excretion in a laxative- abusing patient." Postgrad Med J, 56, p. 862-4
5. Schindler AM (1984) "Isolated neonatal hypomagnesaemia associated with maternal overuse of stool softener" Lancet, 2, p. 822
6. Prior J, White I (1978) "Tetany and clubbing in patient who ingested large quantities of senna [letter." Lancet, 2, p. 947
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Further information
Senokot S side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.