Skip to main content


Generic name: docusate and sennaDOK-yoo-sate-and-SEN-a ]
Brand names: Colace 2-in-1, Dok Plus, Peri-Colace, Senexon-S, Senna Plus, ... show all 10 brands
Drug class: Laxatives

Medically reviewed by on Mar 7, 2023. Written by Cerner Multum.

What is Senexon-S?

Docusate is a stool softener. Senna is a laxative.

Senexon-S is a combination medicine used to treat occasional constipation.

Senexon-S may also be used for purposes not listed in this medication guide.


Use exactly as directed on the label, or as prescribed by your doctor.

Before taking this medicine

You should not use Senexon-S if you are allergic to docusate or senna, or if you are also taking mineral oil.

Ask a doctor or pharmacist if this medicine is safe to use if you have ever had:

Ask a doctor before using this medicine if you are pregnant or breastfeeding.

Do not give this medicine to a child younger than 2 years old without medical advice.

How should I use Senexon-S?

Use exactly as directed on the label, or as prescribed by your doctor.

Take Senexon-S with a full glass of water.

It may be best to take this medicine at night or at bedtime. Senexon-S should cause you to have a bowel movement within 6 to 12 hours.

Do not take Senexon-S for longer than 7 days in a row, unless your doctor tells you to.

Call your doctor if your constipation does not improve or if it gets worse after taking Senexon-S.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Since Senexon-S is used when needed, you may not be on a dosing schedule. Skip any missed dose if it's almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, stomach pain, or diarrhea.

What should I avoid while using Senexon-S?

Ask a doctor or pharmacist before using any other laxative or other stool softener that may contain ingredients similar to docusate or senna.

Senexon-S side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Senexon-S may cause serious side effects. Stop using Senexon-S and call your doctor at once if you have:

  • rectal bleeding;

  • severe stomach pain, nausea, vomiting; or

  • no bowel movement.

Common side effects of Senexon-S may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Senexon-S?

Other drugs may affect Senexon-S, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.