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Satralizumab Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 13, 2024.

Applies to satralizumab: subcutaneous solution.

Serious side effects of satralizumab

Along with its needed effects, satralizumab may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking satralizumab:

More common side effects

  • black, tarry stools
  • body aches or pain
  • burning feeling in the chest or stomach
  • chills
  • cough
  • dark urine
  • depression
  • difficulty in moving
  • dryness or soreness of the throat
  • ear congestion
  • falls
  • fever
  • headache
  • hoarseness
  • indigestion
  • joint pain
  • light-colored stools
  • loss of voice
  • lower back or side pain
  • muscle pain or stiffness
  • nausea and vomiting
  • painful or difficult urination
  • pain, redness, swelling, tenderness, or warmth on the skin
  • pale skin
  • skin rash, hives, itching
  • sneezing
  • sore throat
  • stomach upset
  • stuffy or runny nose
  • tenderness in the stomach area
  • tender, swollen glands in the neck
  • trouble breathing or swallowing
  • ulcers, sores, or white spots in the mouth
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • upper right stomach pain
  • weight gain
  • yellow eyes and skin

Other side effects of satralizumab

Some side effects of satralizumab may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common side effects

  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site

For healthcare professionals

Applies to satralizumab: subcutaneous solution.

General adverse events

The most common adverse reactions (15% or greater) were nasopharyngitis, headache, upper respiratory tract infection, gastritis, rash, arthralgia, extremity pain, fatigue, and nausea.[Ref]

Immunologic

Local

Musculoskeletal

Metabolic

Psychiatric

Hepatic

Respiratory

Other

Hematologic

Nervous system

Dermatologic

Gastrointestinal

References

1. (2020) "Product Information. Enspryng (satralizumab)." Genentech

Further information

Satralizumab side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.