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Rosula NS Side Effects

Generic name: sulfacetamide sodium/urea topical

Note: This document contains side effect information about sulfacetamide sodium/urea topical. Some dosage forms listed on this page may not apply to the brand name Rosula NS.

Applies to sulfacetamide sodium/urea topical: topical lotion, topical pad.


Hypersensitivity side effects, including irritation, have been reported rarely.

Hypersensitivity side effects associated with sulfonamides, including topical sulfonamides, have included Stevens-Johnson syndrome and toxic epidermal necrolysis. A case of local hypersensitivity which progressed to a fatal syndrome resembling systemic lupus erythematosus has also been reported. Sensitization may recur upon reexposure to sulfonamides by different routes of administration.[Ref]


Hematologic side effects associated with sulfonamides have included agranulocytosis, aplastic anemia, and other blood dyscrasias.[Ref]


Hepatic side effects associated with sulfonamides have included fulminant hepatic necrosis.[Ref]


1. "Product Information. Carmol Scalp (sulfacetamide sodium-urea topical)." Doak Dermatologics Division (2022):

2. "Product Information. Rosula NS (sulfacetamide sodium-urea topical)." Doak Dermatologics Division (2022):

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.