Romazicon Side Effects
Generic name: flumazenil
Medically reviewed by Drugs.com. Last updated on Jul 22, 2021.
Note: This document contains side effect information about flumazenil. Some of the dosage forms listed on this page may not apply to the brand name Romazicon.
For the Consumer
Applies to flumazenil: parenteral injection
Side effects include:
For Healthcare Professionals
Applies to flumazenil: intravenous solution
Very common (10% or more): Dizziness (vertigo, ataxia) (10%)
Common (1% to 10%): Headache, paresthesia (sensation abnormal, hypoesthesia)
Frequency not reported: Convulsions, somnolence, speech disorder (dysphonia, thick tongue)[Ref]
Convulsions have occurred in patients with severe hepatic impairment, inpatients relying on benzodiazepine effects to control seizures, patients physically dependent on benzodiazepines, and those who have ingested large doses of other drugs (mixed-drug overdose).[Ref]
Common (1% to 10%): Agitation (anxiety, nervousness, dry mouth, tremor, palpitations, insomnia, dyspnea, hyperventilation), emotional lability (crying abnormal, depersonalization, euphoria, increased tears, depression, dysphoria, paranoia)
Frequency not reported: Confusion (difficulty concentrating, delirium)
Common (1% to 10%): Cutaneous vasodilation (sweating, flushing, hot flushes)
The majority of deaths occurred in patients with serious underlying disease or in patients who had injects large amounts of non-benzodiazepine drugs (usually cyclic antidepressants) as part of an overdose.
Common (1% to 10%): Fatigue (asthenia, malaise)
Frequency not reported: Death, abnormal hearing (transient hearing impairment, hyperacusis, tinnitus), rigors, shivering
Postmarketing reports: Withdrawal symptoms[Ref]
Common (1% to 10%): Injection site pain, injection site reaction (thrombophlebitis, skin abnormality, rash)[Ref]
Common (1% to 10%): Abnormal vision (visual field defect, diplopia)[Ref]
Frequency not reported: Hiccup[Ref]
More about Romazicon (flumazenil)
Related treatment guides
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Some side effects may not be reported. You may report them to the FDA.