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Riboflavin ophthalmic Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 18, 2023.

Applies to riboflavin ophthalmic: ophthalmic solution.

Serious side effects

Along with its needed effects, riboflavin ophthalmic may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking riboflavin ophthalmic:

More common

Less common

Other side effects

Some side effects of riboflavin ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Less common

For Healthcare Professionals

Applies to riboflavin ophthalmic: ophthalmic solution.

General

The most commonly reported side effects include corneal opacity, punctate keratitis, corneal striae and corneal epithelium defect.[Ref]

Ocular

Very common (10% or more): Corneal opacity/haze (up to 71%), corneal epithelium defect (up to 28%), eye pain (up to 26%), punctate keratitis (up to 25%), corneal striae (up to 24%), photophobia (up to 19%), blurred vision (up to 17%), foreign body sensation in eyes (up to 15%), dry eye (up to 14%), ocular hyperemia (up to 14%), reduced visual acuity (up to 11%)

Common (1% to 10%): Anterior chamber cell, anterior chamber flare, corneal disorder, asthenopia, corneal edema, diplopia, eye discharge, eye edema, eye pruritus, eyelid edema, glare, halo vision, keratitis, increased lacrimation, Meibomian gland dysfunction, ocular discomfort, visual impairment, vitreous detachment

Frequency not reported: Blepharitis, corneal thinning[Ref]

Nervous system

Common (1% to 10%): Headache[Ref]

Other

Common (1% to 10%): Eye complication associated with device[Ref]

References

1. Product Information. Photrexa (riboflavin ophthalmic). Avedro, Inc. 2016.

2. Product Information. Photrexa Viscous (riboflavin ophthalmic). Avedro, Inc. 2016.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.