Reblozyl Side Effects
Generic name: luspatercept
Medically reviewed by Drugs.com. Last updated on Oct 20, 2024.
Note: This document provides detailed information about Reblozyl.
Applies to luspatercept: parenteral injection for sub-q use Side Effects associated with luspatercept. Some dosage forms listed on this page may not apply specifically to the brand name Reblozyl.
Applies to luspatercept: parenteral injection for sub-q use.
Side effects include:
Most common (>10%) adverse reactions: fatigue, headache, musculoskeletal pain, arthralgia, dizziness/vertigo, nausea, diarrhea, cough, abdominal pain, dyspnea, COVID-19, peripheral edema, hypertension, hypersensitivity.
For healthcare professionals
Applies to luspatercept: subcutaneous powder for injection.
Hepatic adverse events
- Very common (10% or more): Total bilirubin 2 or more times the upper limit of normal (ULN) (64%), alanine aminotransferase 3 or more times ULN (12%), aspartate aminotransferase 3 or more times ULN (11%)
- Common (1% to 10%): Alkaline phosphatase 2 or more times ULN, direct bilirubin 2 or more times ULN[Ref]
Cardiovascular
- Common (1% to 10%): Hypertension, deep vein thrombosis[Ref]
Nervous system
- Very common (10% or more): Headache (26%), dizziness (11%)
- Common (1% to 10%): Cerebrovascular accident[Ref]
Musculoskeletal
- Very common (10% or more): Bone pain (20%), arthralgia (19%)[Ref]
Gastrointestinal
- Very common (10% or more): Abdominal pain (14%), diarrhea (12%)
- Common (1% to 10%): Nausea[Ref]
Metabolic
- Common (1% to 10%): Hyperuricemia[Ref]
Respiratory
- Very common (10% or more): Cough (14%)[Ref]
Immunologic
Other
- Very common (10% or more): Fatigue (14%)
- Frequency not reported: Death (due to unconfirmed acute myelogenous leukemia)[Ref]
See also:
Revlimid
Revlimid is used to treat types of multiple myeloma, mantle cell lymphoma, follicular lymphoma and ...
Vitamin B6
Vitamin B6 is used for anemia, dietary supplementation, drug induced vitamin/mineral deficiency ...
Botox
Botox is used for cosmetic purposes and to treat overactive bladder symptoms, urinary incontinence ...
Procrit
Procrit is a man-made protein used to treat anemia caused by chronic kidney disease, chemotherapy ...
Epogen
Epogen is used to treat anemia (a lack of red blood cells in the body). Learn about side effects ...
Retacrit
Retacrit is used for anemia, anemia due to chronic kidney disease, anemia prior to surgery, anemia ...
Azacitidine
Azacitidine systemic is used for acute myeloid leukemia, myelodysplastic syndrome
Epoetin alfa
Epoetin alfa systemic is used for anemia, anemia due to chronic kidney disease, anemia prior to ...
Lenalidomide
Lenalidomide (Revlimid) is used to treat multiple myeloma, mantle cell lymphoma, follicular ...
Ferrous gluconate
Ferrous gluconate systemic is used for anemia, anemia due to chronic kidney disease, iron ...
References
1. (2019) "Product Information. Reblozyl (luspatercept)." Celgene Corporation
More about Reblozyl (luspatercept)
- Check interactions
- Compare alternatives
- Pricing & coupons
- Reviews (6)
- Drug images
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: miscellaneous erythropoiesis agents
- Breastfeeding
- En español
Patient resources
Professional resources
Related treatment guides
Further information
Reblozyl side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.