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Quadracel Side Effects

Generic name: diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

Medically reviewed by Drugs.com. Last updated on Jan 6, 2024.

Note: This document contains side effect information about diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid. Some dosage forms listed on this page may not apply to the brand name Quadracel.

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension.

Serious side effects of Quadracel

Along with its needed effects, diphtheria toxoid/pertussis, acellular/poliovirus vaccine, inactivated/tetanus toxoid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking diphtheria toxoid/pertussis, acellular/poliovirus vaccine, inactivated/tetanus toxoid:

Rare

Incidence not known

Other side effects of Quadracel

Some side effects of diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

For Healthcare Professionals

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension.

Local

Very common (10% or more): Injection site pain (77.4%), change in limb circumference (68.1%), injection site erythema (59.1%), injection site swelling (40.2%)

Common (1% to 10%): Extensive limb swelling

Postmarketing reports: Injection site reactions (including inflammation, mass, sterile abscess, and edema), large injection site reactions (over 50 mm) including limb swelling from the injection site beyond one or both joints, injection site cellulitis, injection site abscess[Ref]

Hypersensitivity

Postmarketing reports: Anaphylactic reaction, hypersensitivity, allergic reactions (including rash, urticaria, dyspnea)[Ref]

Other

Very common (10% or more): Malaise (35%)

Postmarketing reports: Listlessness[Ref]

Nervous system

Very common (10% or more): Headache (15.6%)

Postmarketing reports: Somnolence, convulsion, febrile convulsion, hypotonic-hyporesponsive episode (HHE), hypotonia[Ref]

Cardiovascular

Postmarketing reports: Cyanosis, pallor[Ref]

Psychiatric

Postmarketing reports: Screaming[Ref]

Musculoskeletal

Very common (10% or more): Myalgia (53.8%)[Ref]

More about Quadracel (diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid)

Patient resources

Other brands

Kinrix

Professional resources

Other brands

Kinrix

Related treatment guides

References

1. Product Information. Quadracel (DTaP-IPV) (diphtheria/pertussis,acel/tetanus/polio). sanofi pasteur. 2015.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.