Pneumococcal 15-valent Conjugate Vaccine Side Effects

Medically reviewed by Drugs.com. Last updated on Nov 11, 2024.

Applies to pneumococcal 15-valent conjugate vaccine: intramuscular suspension.

Precautions

Be sure to notify your doctor of any side effects that occur after you receive this vaccine.

This vaccine will not protect you against all types of pneumococcal infections. It will also not treat an active infection.

This vaccine may cause serious allergic reactions, including anaphylaxis, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, a fast heartbeat, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving the vaccine.

This vaccine may cause breathing problems (eg, apnea) in premature babies. Check with your doctor right away if your baby has bluish lips or skin or not breathing.

Tell your doctor if you are using a medicine that causes a weak immune system.

Other side effects

Some side effects of pneumococcal 15-valent conjugate vaccine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects

Along with its needed effects, pneumococcal 15-valent conjugate vaccine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking pneumococcal 15-valent conjugate vaccine:

For healthcare professionals

Applies to pneumococcal 15-valent conjugate vaccine: intramuscular suspension.

General adverse events

The most commonly reported side effects included localized pain, irritability, elevated body temperature (from at least 38C to less than 39C), and somnolence.^[Ref]

Dermatologic

• Common (1% to 10%): Urticaria^[Ref]

Local

• Very common (10% or more): Localized pain (up to 75.8%), localized erythema (up to 21.6%), localized swelling (up to 21.7%), localized induration (up to 14.1%)
• Uncommon (0.1% to 1%): Injection site urticaria^[Ref]

Metabolic

• Very common (10% or more): Decreased appetite (up to 19.4%)^[Ref]

Musculoskeletal

• Very common (10% or more): Myalgia (up to 28.8%), arthralgia (up to 12.7%)^[Ref]

Nervous system

• Very common (10% or more): Somnolence (up to 40.7%), headache (up to 26.5%)^[Ref]

Other

• Very common (10% or more): Elevated body temperature (at least 38C to less than 39C [up to 50.8%]), fatigue (up to 34.3%)
• Common (1% to 10%): Elevated body temperature (at least 39C to less than 40C), elevated body temperature (at least 40C)^[Ref]

Psychiatric

• Very common (10% or more): Irritability (up to 55.1%)
• Common (1% to 10%): Extreme distress, unable to do unusual activities^[Ref]

See also:

Further information

Pneumococcal 15-valent conjugate vaccine side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer