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Peramivir Side Effects

For the Consumer

Applies to peramivir: intravenous solution, solution iv (infusion)

As well as its needed effects, peramivir may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking peramivir, check with your doctor or nurse immediately:

  • Blistering, peeling, or loosening of the skin
  • chills
  • cough
  • diarrhea
  • fever
  • itching
  • joint or muscle pain
  • red, irritated eyes
  • sore throat
  • sores, ulcers, or white spots in the mouth or on the lips
  • unusual tiredness or weakness
Incidence not known:
  • Confusion as to time, place, or person
  • holding false beliefs that cannot be changed by fact
  • red skin lesions, often with a purple center
  • seeing, hearing, or feeling things that are not there
  • unusual excitement, nervousness, or restlessness

Minor Side Effects

Some peramivir side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

Less common:
  • Blurred vision
  • difficulty having a bowel movement (stool)
  • dizziness
  • headache
  • nervousness
  • pounding in the ears
  • slow or fast heartbeat
  • trouble sleeping

For Healthcare Professionals

Applies to peramivir: intravenous solution


Common (1% to 10%): Hypertension[Ref]


Common (1% to 10%): Constipation, diarrhea[Ref]


Common (1% to 10%): AST increased, ALT greater than 2.5 times the upper limit of normal (ULN)[Ref]


Postmarketing reports: Steven-Johnson Syndrome, exfoliative dermatitis, rash[Ref]


Common (1% to 10%): Neutrophils less than 1 x 10(9)/L[Ref]


Common (1% to 10%): Serum glucose greater than 160 mg/dL[Ref]


Common (1% to 10%): Creatine phosphokinase 6 x ULN or greater[Ref]


Common (1% to 10%): Insomnia
Postmarketing reports: Delirium, hallucination[Ref]


1. "Product Information. Rapivab (peramivir)." BioCryst Pharmaceuticals Inc, Durham, NC.

It is possible that some side effects of peramivir may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.