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Mononine Side Effects

Generic name: coagulation factor ix

Medically reviewed by Drugs.com. Last updated on Feb 27, 2024.

Note: This document contains side effect information about coagulation factor ix. Some dosage forms listed on this page may not apply to the brand name Mononine.

Applies to coagulation factor ix: intravenous powder for solution.

Serious side effects of Mononine

Along with its needed effects, coagulation factor ix (the active ingredient contained in Mononine) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking coagulation factor ix:

More common

Less common

Incidence not known

Other side effects of Mononine

Some side effects of coagulation factor ix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

For Healthcare Professionals

Applies to coagulation factor ix: intravenous kit, intravenous powder for injection.

Hypersensitivity

Frequency not reported: Hypersensitivity (including bronchospastic reactions and/or hypotension, anaphylaxis, development of high-titer inhibitors necessitating alternative treatment)[Ref]

Hematologic

Common (1% to 10%): Factor IX inhibition[Ref]

Gastrointestinal

Common (1% to 10%): Nausea, vomiting[Ref]

Dermatologic

Common (1% to 10%): Rash pruritic, hives[Ref]

Local

Common (1% to 10%): Injection site discomfort, injection site pain[Ref]

Nervous system

Common (1% to 10%): Headache, dysgeusia, lethargy, dizziness, shaking, drowsiness[Ref]

Respiratory

Common (1% to 10%): Dry cough, hypoxia, chest tightness, dyspnea[Ref]

Renal

The renal infarct occurred in a hepatitis C antibody positive patients 12 days after treatment of a bleeding episode; the relation of the infarct to the prior administration of this drug is uncertain.[Ref]

Common (1% to 10%): Renal infarct[Ref]

Ocular

Common (1% to 10%): Blurred vision[Ref]

Immunologic

Common (1% to 10%): Influenza, cellulitis at injection site, phlebitis at injection site[Ref]

Psychiatric

Common (1% to 10%): Apathy, depression[Ref]

Other

Common (1% to 10%): Hemophilia (lack of efficacy), asthenia, fever, chills[Ref]

Cardiovascular

Common (1% to 10%): Flushing[Ref]

References

1. Product Information. Benefix (coagulation factor IX). Wyeth Laboratories. 2022.

2. Product Information. Ixinity (coagulation factor IX). Cangene bioPharma, Inc. 2022.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.