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Metyrapone Side Effects

Applies to metyrapone: oral capsule, oral tablet

In addition to its needed effects, some unwanted effects may be caused by metyrapone. In the event that any of these side effects do occur, they may require medical attention.

Major Side Effects

You should check with your doctor immediately if any of these side effects occur when taking metyrapone:

Rare (with long-term use)
  • Irregular heartbeat

Severity: Moderate

If any of the following side effects occur while taking metyrapone, check with your doctor or nurse as soon as possible:

Less common:
  • Skin rash
Rare (usually with long-term use)
  • Enlargement of clitoris
  • muscle cramps or pain
  • sore throat or fever
  • swelling of feet or lower legs
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • weight gain (rapid)
Symptoms of overdose:
  • Abdominal or stomach pain (severe)
  • confusion
  • decrease in consciousness
  • diarrhea (severe)
  • nausea (severe)
  • nervousness
  • unusual thirst
  • vomiting (severe)
  • weakness (sudden)

Minor Side Effects

Some of the side effects that can occur with metyrapone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common:
  • Dizziness
  • drowsiness
  • headache
  • lightheadedness
  • nausea
Rare
  • Confusion or mental slowing
  • excessive hair growth
  • greater-than-normal loss of scalp hair
  • increased sweating
  • loss of appetite
  • upper abdominal or stomach pain
  • vomiting
  • worsening of acne

Not all side effects for metyrapone may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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