Kinrix Side Effects

Generic name: diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid

Medically reviewed by Drugs.com. Last updated on Apr 15, 2025.

Note: This document provides detailed information about Kinrix Side Effects associated with diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid. Some dosage forms listed on this page may not apply specifically to the brand name Kinrix.

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension.

Precautions

It is very important that the doctor check your child at regular visits to make sure this vaccine is working properly and to check for unwanted effects.

Tell your child’s doctor about all other vaccines your child has had, especially if those vaccines were part of a series. This vaccine might be used to finish a series of vaccines.

Contact your doctor immediately if your child has sudden weakness in the arms and legs. This could be a sign of a serious condition called Guillain-Barré syndrome.

This vaccine will not treat an active infection. If your child has an infection due to diphtheria, tetanus, pertussis, or polio, your child will need medicines to treat these infections.

Fainting may occur after you receive this vaccine. You may also have vision changes, numbness or tingling in your arms, hands, or feet, or jerky movements of the arms and legs. Call the doctor right away if you or your child have any of these symptoms.

Be sure to tell your child’s doctor about any serious side effects that occur after your child receives the vaccine. This may include seizures, a high fever, crying that will not stop, or severe redness or swelling where the shot was given.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Common side effects of Kinrix

Some side effects of diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Serious side effects of Kinrix

Along with its needed effects, diphtheria toxoid/pertussis, acellular/poliovirus vaccine, inactivated/tetanus toxoid may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid:

For healthcare professionals

Applies to diphtheria toxoid / pertussis, acellular / poliovirus vaccine, inactivated / tetanus toxoid: intramuscular suspension.

Local adverse events

• Very common (10% or more): Injection site pain (77.4%), change in limb circumference (68.1%), injection site erythema (59.1%), injection site swelling (40.2%)
• Common (1% to 10%): Extensive limb swelling
• Postmarketing reports: Injection site reactions (including inflammation, mass, sterile abscess, and edema), large injection site reactions (over 50 mm) including limb swelling from the injection site beyond one or both joints, injection site cellulitis, injection site abscess^[Ref]

Hypersensitivity

• Postmarketing reports: Anaphylactic reaction, hypersensitivity, allergic reactions (including rash, urticaria, dyspnea)^[Ref]

Other

• Very common (10% or more): Malaise (35%)
• Postmarketing reports: Listlessness^[Ref]

Nervous system

• Very common (10% or more): Headache (15.6%)
• Postmarketing reports: Somnolence, convulsion, febrile convulsion, hypotonic-hyporesponsive episode (HHE), hypotonia^[Ref]

Cardiovascular

• Postmarketing reports: Cyanosis, pallor^[Ref]

Psychiatric

• Postmarketing reports: Screaming^[Ref]

Musculoskeletal

• Very common (10% or more): Myalgia (53.8%)^[Ref]

See also:

Further information

Kinrix side effects can vary depending on the individual. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Note: Medication side effects may be underreported. If you are experiencing side effects that are not listed, submit a report to the FDA by following this guide.

Medical Disclaimer