Kalbitor Side Effects
Generic Name: ecallantide
Note: This document contains side effect information about ecallantide. Some of the dosage forms listed on this page may not apply to the brand name Kalbitor.
In Summary
More frequent side effects include: pruritus. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to ecallantide: subcutaneous solution
Warning
Subcutaneous route (Solution)
Anaphylaxis has been reported after administration of ecallantide. Because of this risk, ecallantide should only be administered by a healthcare professional who is aware of the similarity of symptoms between anaphylaxis and hereditary angioedema and who has the appropriate medical support to manage both conditions. Patients should be monitored closely.
Along with its needed effects, ecallantide (the active ingredient contained in Kalbitor) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking ecallantide:
Less Common
- Blurred vision
- chest discomfort
- confusion
- cough
- difficulty with breathing
- difficulty with swallowing
- dizziness
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast heartbeat
- feeling of warmth
- fever
- hives or welts, itching, or skin rash
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- redness of the face, neck, arms, and occasionally, upper chest
- redness of the skin
- runny nose
- sneezing
- stuffy nose
- sweating
- throat irritation
- tightness in the chest
- unusual tiredness or weakness
Some side effects of ecallantide may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More Common
Less Common
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
- muscle aches
- nausea
- sore throat
For Healthcare Professionals
Applies to ecallantide: subcutaneous solution
General
The most common adverse reactions were headache, nausea, diarrhea, pyrexia, injection site reactions, and nasopharyngitis.[Ref]
Dermatologic
Common (1% to 10%): Pruritus, rash, urticaria[Ref]
Gastrointestinal
Very common (10% or more): Nausea (up to 13%), diarrhea (up to 11%)
Common (1% to 10%): Vomiting, upper abdominal pain[Ref]
Hypersensitivity
Common (1% to 10%): Anaphylaxis
Frequency not reported: Hypersensitivity reactions[Ref]
Local
Common (1% to 10%): Injection site reactions[Ref]
Nervous system
Very common (10% or more): Headache (up to 16%)[Ref]
Other
Very common (10% or more): Fatigue (12%)[Ref]
Respiratory
Common (1% to 10%): Upper respiratory tract infection, nasopharyngitis[Ref]
References
1. "Product Information. Kalbitor (ecallantide)." Dyax Corporation, Cambridge, MA.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
More about Kalbitor (ecallantide)
- During Pregnancy
- Dosage Information
- Compare Alternatives
- Pricing & Coupons
- En Español
- 1 Review
- Drug class: miscellaneous coagulation modifiers
- FDA Approval History
