Hydrocortisone / neomycin / polymyxin b topical Side Effects
For the Consumer
Applies to hydrocortisone / neomycin / polymyxin b topical: external cream
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Skin changes (pimples, stretch marks, slow healing, hair growth).
- Very bad skin irritation.
What are some other side effects of this drug?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Skin irritation.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
For Healthcare Professionals
Applies to hydrocortisone / neomycin / polymyxin b topical: topical cream
Dermatologic side effects associated with the use of topical corticosteroids have included burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. These reactions are more likely with the use of occlusive dressings or with long-term use.[Ref]
Hypersensitivity reactions have been associated with the anti-infective component of this drug and are manifested by itching and swelling. Neomycin is known to cause contact sensitivity with an estimated incidence of 0.09% to 1%.[Ref]
Nervous system side effects have included ototoxicity associated with the use of neomycin.[Ref]
Renal side effects have included nephrotoxicity associated with the use of neomycin.[Ref]
1. "Product Information. Cortisporin Topical (hydrocortisone/neomycin/polymyxin B topical)." Monarch Pharmaceuticals Inc, Bristol, TN.
Some side effects of hydrocortisone / neomycin / polymyxin b topical may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
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- Drug class: topical steroids with anti-infectives
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