Hetastarch Side Effects
For the Consumer
Applies to hetastarch: parenteral injection
Side effects include:
Hypersensitivity reactions, coagulopathy, hemodilution, circulatory overload, metabolic acidosis, CHF, pulmonary edema, bleeding, vomiting, peripheral edema, submaxillary and parotid glandular enlargement, mild influenza-like symptoms, headache, muscle pain.
For Healthcare Professionals
Applies to hetastarch: intravenous solution
Frequency not reported: Vomiting[Ref]
Frequency not reported: Intracranial bleeding, bleeding and/or anemia due to hemodilution and/or Factor VIII deficiency, acquired von Willebrand's-like syndrome, coagulopathy (including rare cases of disseminated intravascular coagulopathy and hemolysis)[Ref]
Frequency not reported: Death, life-threatening anaphylactic/anaphylactoid reactions, cardiac arrest, ventricular fibrillation, severe hypotension, non-cardiac pulmonary edema, laryngeal edema, bronchospasm, angioedema, wheezing, restlessness, tachypnea, stridor, fever, chest pain, bradycardia, tachycardia, shortness of breath, chills, urticaria, pruritus, facial and periorbital edema, coughing, sneezing, flushing erythema multiforme, rash[Ref]
Frequency not reported: Metabolic acidosis[Ref]
Frequency not reported: Muscle pains[Ref]
Frequency not reported: Submaxillary and parotid glandular enlargement, mild influenza-like symptoms, headaches, hydroxyethyl starch-associated pruritus in patients with deposits of hydroxyethyl starch in peripheral nerves[Ref]
1. "Product Information. Hespan (hetastarch)." B. Braun Medical, Irvine, CA.
2. "Product Information. Hextend (hetastarch)." Abbott Pharmaceutical, Abbott Park, IL.
Some side effects of hetastarch may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
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- Drug class: plasma expanders
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