Applies to the following strength(s): 60 mg/mL-NaCl 0.9% ; 60 mg/mL-LR
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Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Hypovolemia
Dosage for Acute Use in Plasma Volume Expansion: 500 to 1000 mL by intravenous infusion
Maintenance dose: Total dosage and rate of infusion depends on the amount of blood or plasma lost and the resultant hemoconcentration
Maximum dose: Doses of more than 1500 mL per day (approximately 20 mL per kg of body weight) are usually not required although higher doses have been used in postoperative and trauma patients.
Dosage in Leukapheresis: 250 to 700 mL to which citrate anticoagulant has been added and administered to the input line of the centrifugation apparatus at a ratio of 1:8 to 1:13 to venous whole blood.
-Hetastarch and citrate should be thoroughly mixed to assure effective anticoagulation.
-Hetastarch admixtures of 500 to 560 mL with citrate concentrations up to 2.5% are compatible for 24 hours at room temperature.
Renal Dose Adjustments
Data not available
Liver Dose Adjustments
Data not available
Consult WARNINGS section for dosing related precautions
Hemodialysis: Hetastarch not eliminated by hemodialysis
Peritoneal dialysis: Data not available
-Avoid excessive heat. Protect from freezing.
-Exposure to prolonged adverse storage conditions may result in a change to a turbid deep brown color or the formation of a crystalline precipitate in which cases the solution should not be used.
-Storage in automated dispensing machines: Brief exposure up to 2 weeks to ultraviolet or fluorescent light does not affect the product labeling legibility, but prolonged exposure can cause fading of the red label. Rotate stock frequently.
IV compatibility: The safety and compatibility of additive other than citrate have not been studied.
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- Drug class: plasma expanders