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Hepatitis a pediatric vaccine Side Effects

Applies to hepatitis a pediatric vaccine: intramuscular suspension.


Tell your doctor if you use other medicines or have other medical conditions or allergies.

Get emergency medical help if your child has signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Your child should not receive a booster vaccine if he or she had a life-threatening allergic reaction after the first shot.

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shot caused any side effects.

Call your child's doctor at once if the child has:

Common side effects may include:

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to hepatitis a pediatric vaccine: intramuscular suspension.


The most common adverse events were injection site reactions, irritability, drowsiness, loss of appetite and headache.[Ref]


Very common (10% or more): Injection site soreness (56%), injection site pain (37%), injection site redness (22.8%)

Common (1% to 10%): Induration and swelling of the injection site, injection site bruising, injection site ecchymosis

Uncommon (0.1% to 1%): Injection site hematoma

Postmarketing reports: Injection site reaction[Ref]

Nervous system

Very common (10% or more): Headache (23.8%), drowsiness (22.3%),

Uncommon (0.1% to 1%): Dysgeusia, hypertonia, vertigo, seizure

Rare (less than 0.1%): Febrile seizure

Postmarketing reports: Convulsion, dizziness, encephalopathy, Guillain-Barre syndrome, hypoesthesia, multiple sclerosis, myelitis, neuropathy, paresthesia, somnolence, syncope, cerebellar ataxia, encephalitis[Ref]


Very common (10% or more): Fever (16.4%)

Common (1% to 10%): Fatigue, malaise, crying

Uncommon (0.1% to 1%): Creatine phosphokinase increased

Postmarketing reports: Congenital anomaly, influenza-like symptoms[Ref]


Very common (10% or more): Irritability (33.3%)

Common (1% to 10%): Insomnia[Ref]


Very common (10% or more): Loss of appetite (19.9%)

Common (1% to 10%): Anorexia

Rare (less than 0.1%): Dehydration[Ref]


Common (1% to 10%): Upper respiratory tract infection, conjunctivitis, otitis media, nasopharyngitis, viral infection, pharyngitis streptococcal, laryngotracheobronchitis, viral exanthema, gastroenteritis viral, roseola, pharyngitis[Ref]


Common (1% to 10%): Nausea, diarrhea, teething, constipation, vomiting, abdominal pain

Rare (less than 0.1%): Gastroenteritis[Ref]


Common (1% to 10%): Dermatitis diaper, rash vesicular, measles-like rash, varicella-like rash, rash morbilliform

Uncommon (0.1% to 1%): Pruritus, rash, urticaria

Rare (less than 0.1%): Cellulitis

Postmarketing reports: Angioedema, erythema multiforme, hyperhidrosis[Ref]


Common (1% to 10%): Myalgia, back pain, stiffness

Uncommon (0.1% to 1%): Arthralgia

Postmarketing reports: Musculoskeletal stiffness, chills[Ref]


Uncommon (0.1% to 1%): Allergic reactions (including injection site pruritus/rash, bronchial constriction, asthma, wheezing, edema/swelling, rash, generalized erythema, urticaria, pruritus, eye irritation/itching, dermatitis)

Postmarketing reports: Anaphylactic reaction, anaphylactoid reaction, serum sickness-like syndrome[Ref]


Uncommon (0.1% to 1%): Lymphadenopathy

Postmarketing reports: Thrombocytopenia[Ref]


Postmarketing reports: Hepatitis, jaundice[Ref]


Postmarketing reports: Vasculitis[Ref]


Uncommon (0.1% to 1%): Photophobia[Ref]


Common (1% to 10%): Rhinorrhea, cough, nasal congestion, respiratory congestion

Postmarketing reports: Dyspnea[Ref]


1. "Product Information. Havrix (HepA) (hepatitis A adult vaccine)." SmithKline Beecham

2. (2022) "Product Information. Vaqta (hepatitis A adult vaccine)." Merck & Co., Inc

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.