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hepatitis A pediatric vaccine

Generic Name: hepatitis A pediatric vaccine (HEP a TYE tis)
Brand Name: Havrix Pediatric, Vaqta Pediatric

What is hepatitis A pediatric vaccine?

Hepatitis is a serious disease caused by a virus. Hepatitis causes inflammation of the liver, vomiting, and jaundice (yellowing of the skin or eyes). Hepatitis can lead to liver cancer, cirrhosis, or death.

Hepatitis A is spread through contact with the stool (bowel movements) of a person infected with the hepatitis A virus. This usually occurs by eating food or drinking water that has become contaminated as a result of handling by an infected person.

The hepatitis A pediatric vaccine is used to help prevent this disease in children.

This vaccine works by exposing your child to a small amount of the virus, which causes the body to develop immunity to the disease. This vaccine will not treat an active infection that has already developed in the body.

Vaccination with hepatitis A pediatric vaccine is recommended for all children who are 12 months of age or older. This vaccine is also recommended in children who travel to certain areas of the world where hepatitis A is a common disease.

Other risk factors for hepatitis in children include: receiving treatment for hemophilia or other bleeding disorders, or being in an area where there has been an outbreak of hepatitis A.

Like any vaccine, the hepatitis A pediatric vaccine may not provide protection from disease in every person.

What is the most important information I should know about this vaccine?

You should not receive this vaccine if you have ever had a life-threatening allergic reaction to any vaccine containing hepatitis A, or if you are allergic to neomycin.

What should I discuss with my healthcare provider before receiving this vaccine?

Hepatitis A pediatric vaccine will not protect against infection with hepatitis B, C, and E, or other viruses that affect the liver. It may also not protect against hepatitis A if your child is already infected with the virus, even without showing symptoms.

Your child should not receive this vaccine if he or she has ever had a life-threatening allergic reaction to any vaccine containing hepatitis A, or if the child is allergic to neomycin.

Before receiving this vaccine, tell the doctor if your child has:

  • an allergy to latex rubber; or

  • a weak immune system (caused by disease or by using certain medicine.

Your child can still receive a vaccine if he or she has a minor cold. In the case of a more severe illness with a fever or any type of infection, wait until the child gets better before receiving this vaccine.

Hepatitis A vaccine is not approved for use by anyone younger than 12 months old.

How is this vaccine given?

This vaccine is given as an injection (shot) into a muscle. Your child will receive this injection in a doctor's office or other clinic setting.

The hepatitis A pediatric vaccine is given in a series of 2 shots. The first shot is usually given when the child is between 12 and 23 months old. The booster shot is then given 6 months later.

Your child's individual booster schedule may be different from these guidelines. Follow your doctor's instructions or the schedule recommended by your local health department.

To prevent hepatitis A while traveling, the child should receive this vaccine at least 2 weeks before the trip. Your child's doctor will determine the best dosing schedule for your situation.

Your doctor may recommend treating fever and pain with an aspirin free pain reliever such as acetaminophen (Tylenol) or ibuprofen (Motrin, Advil, and others) when the shot is given and for the next 24 hours. Follow the label directions or your doctor's instructions about how much of this medicine to use.

What happens if I miss a dose?

Contact your doctor if you will miss a booster dose or if you get behind schedule. The next dose should be given as soon as possible. There is no need to start over.

Be sure your child receives all recommended doses of this vaccine, or the child may not be fully protected against disease.

What happens if I overdose?

An overdose of this vaccine is unlikely to occur.

What should I avoid before or after receiving this vaccine?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Hepatitis A pediatric vaccine side effects

Get emergency medical help if your child has signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Your child should not receive a booster vaccine if he or she had a life-threatening allergic reaction after the first shot.

Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shot caused any side effects.

Becoming infected with hepatitis A is much more dangerous to your child's health than receiving the vaccine to protect against it. Like any medicine, this vaccine can cause side effects, but the risk of serious side effects is extremely low.

Call your child's doctor at once if the child has:

  • extreme drowsiness, fainting;

  • fussiness, irritability, crying for an hour or longer;

  • seizure (blackout-out or convulsions); or

  • high fever (within a few hours or a few days after the vaccine).

Common side effects may include:

  • low fever, general ill feeling;

  • nausea, loss of appetite;

  • headache; or

  • swelling, tenderness, redness, warmth, or a hard lump where the shot was given.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report vaccine side effects to the US Department of Health and Human Services at 1-800-822-7967.

See also: Side effects (in more detail)

Hepatitis A pediatric vaccine dosing information

Usual Pediatric Dose for Hepatitis A Prophylaxis:

1 years to 18 years:
hepatitis A pediatric vaccine 720 units/0.5 mL intramuscular suspension:
720 units/0.5 mL intramuscularly followed by 720 units/0.5 mL intramuscularly given anytime between 6 to 12 months after primary course.


hepatitis A pediatric vaccine 25 units/0.5 mL intramuscular suspension:
25 units/0.5 mL intramuscularly followed by 25 units/0.5 mL intramuscularly given anytime between 6 to 12 months after primary course.

What other drugs will affect hepatitis A pediatric vaccine?

Before receiving this vaccine, tell the doctor about all other vaccines your child has recently received.

Also tell the doctor if your child has recently received drugs or treatments that can weaken the immune system, including:

  • an oral, nasal, inhaled, or injectable steroid medicine;

  • medications to treat psoriasis, rheumatoid arthritis, or other autoimmune disorders; or

  • medicines to treat or prevent organ transplant rejection.

If your child is using any of these medications, he or she may not be able to receive the vaccine, or may need to wait until the other treatments are finished.

This list is not complete. Other drugs may interact with this vaccine, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.

Where can I get more information?

  • Your doctor or pharmacist can provide more information about this vaccine. Additional information is available from your local health department or the Centers for Disease Control and Prevention.
  • Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 6.01.

Date modified: October 14, 2016
Last reviewed: August 02, 2016